Behandlung und kontrolle primärer kardiovaskulärer risikofaktoren in den alten bundesländern

Laaser, Ulrich; Lemke-Goliasch, Peter; Schumann, Volker; Kaftan, Sonja; Hellmeier, Wolfgang

doi:10.1007/bf02956070

Cited by 5 publications

(2 citation statements)

References 7 publications

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“…A long period from infection and colonization to disease development may also affect differences in the genetic profile of the NTM isolates from patients compared to those from the environment [81]. Despite these difficulties, a study by Kaustova et al (1993) showed a connection between M. xenopi human isolates and contaminated household water in the Ostrava district in a study covering the period 1990–1991 [84].…”

Section: Discussionmentioning

confidence: 99%

Socio-Economic and Environmental Factors Related to Spatial Differences in Human Non-Tuberculous Mycobacterial Diseases in the Czech Republic

Modrá

Ulmann

Caha

et al. 2019

IJERPH

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Non-tuberculous mycobacteria (NTM) are ubiquitous environmental bacteria that can induce pulmonary and non-pulmonary diseases in susceptible persons. It is reported that the prevalence of NTM diseases is increasing in developed countries, but this differs by regions and countries. NTM species distribution and the rate of diseases caused by NTM vary widely in the historical territories of Moravia and Silesia (Czech Republic). This epidemiologic study of NTM diseases covers the period 2012–2018, reviews isolates obtained from patients with clinical disease and investigates correlations with related socio-economic and environmental factors. Individual NTM patients were included only once during the studied period and results were presented as incidence rate per year. The most frequently isolated NTM meeting the microbiological and clinical criteria in the study were the Mycobacterium avium-intracellulare complex, followed by Mycobacterium kansasii and Mycobacterium xenopi. A previously described endemic incidence of M. kansasii in the Karviná district and M. xenopi in the Ostrava district was also observed in this study. The incidence of NTM patients in the whole studied territory was 1.10/100,000 inhabitants (1.33/100,000 in men and 0.88/100,000 in women). The annual incidence of lymphadenitis in children (≤5 years of age) was 2.35/100,000 of the population of children during the 7 year period but increased in the year 2018 to 5.95/100,000. The rate of human tuberculosis in the studied area was 1.97/100,000 inhabitants. The incidence of NTM pulmonary diseases correlated with a lower socio-economic status (r = 0.63) and a higher concentration of benzo[a]pyrene pollution in the air (r = 0.64).

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Section: Discussionmentioning

confidence: 99%

Socio-Economic and Environmental Factors Related to Spatial Differences in Human Non-Tuberculous Mycobacterial Diseases in the Czech Republic

Modrá

Ulmann

Caha

et al. 2019

IJERPH

View full text Add to dashboard Cite

show abstract

“…In literature, there is a wide range, e.g. up to 65.7% of the actual prevalence, controlled in different studies with larger populations between N = 2,992 and N = 26,913 (Haijar and Kotchen 2003;Jo et al 2001;Laaser et al 1993;Leenen et al 2008;Macedo et al 2005;Meisinger et al 2006;Psaltopoulou et al 2004;Wang et al 2004). In the majority of these studies, control rates between 10 and 20% were found.…”

Section: Introductionmentioning

confidence: 99%