Beetroot Juice Supplementation Increases High Density Lipoprotein-Cholesterol and Reduces Oxidative Stress in Physically Active Individuals

Abstract

Beetroot juice contains a high level of biologically accessible antioxidants, beneficial phytochemicals and dietary nitrate, which seem to exert beneficial effects in human health. Dietary nitrate, from beetroot has been reported to lower blood pressure. However the impact of beetroot on lipid profile and oxidative stress is unknown. In present study, the effect of supplementation with beetroot juice for 15 days was investigated. Plasma lipid profile, antioxidant status, oxidative stress and body composition changes were evaluated at baseline and after 15 days of beetroot juice supplementation. Beetroot juice supplementation beneficially influenced the lipid profile by significantly increasing the levels of high-density lipoprotein cholesterol (HDL-C) from 42.9 ± 8.3 mg/dl to 50.2 ± 9.8 mg/dl and decreasing lowdensity lipoprotein cholesterol (LDL-C) from 129.7 ± 82.3 mg/dl to 119.5 ± 79.2 mg/dl compared with baseline values. Beetroot juice supplementation increased (P < 0.05) plasma nitrite level and guanosine 3', 5'-cyclic monophosphate (c-GMP) levels. A significant increase in plasma total antioxidant capacity and vitamin C levels was observed after beetroot juice intake for 15 days. There was no significant change in the body fat mass and lean body mass of participants with the beetroot juice supplementation. Beetroot juice supplementation significantly decreased the stress markers plasma hydroperoxides and cortisol levels. Beetroot juice acts as a potent vasodilator by increasing plasma c-GMP levels and nitrite levels. Beetroot juice consumption improves plasma lipid profile and antioxidant status, encouraging further evaluation on a population with higher cardiovascular disease risk.

Potential Therapeutic Effects of Beet Root) Beta Vulgaris, L.) Pomace on Nephropathy Diabetic Rats

“…Moreover, nephropathy diabetic rats supplemented with 7.5% BRPP had the highest reduction in the levels of cholesterol, TG and LDL.c and elevation in HDL.c compared to those supplemented with 5% BRPP, while that the level of VLDL.c in nephropathy diabetic rats supplemented with 5% BRPP did not differ from nephropathy diabetic rats supplemented with 7.5% BRPP. These results are in agreement with Singh et al (2015) who showed that the consumption of beet root lowered total cholesterol, triglycerides, LDL˗c levels and increased the levels of HDL˗c in humans. Also, Sardi et al (2009) reported that feeding with 2 g/kg of beet root powder for 10 days resulted in significant changes in serum cholesterol levels and reduction of fatty liver symptoms in a chemically induced diabetic animal model.…”

Acute Beetroot Juice Intake: Hematological, Antioxidant and Lipid Parameters in Female Athletes

“…Their research showed notable changes in triglycerides, cholesterol, and LDL, without any significant change in HDL, which is consistent with the results of the present study [16]. In other studies, researchers reported significant changes in lipid profiles after chronic intake of beetroot juice [22,23]. This information reminds us that the more a person drinks beetroot juice, the more a person may benefit from its antilipid properties.…”

Efficacy of Beetroot Juice Consumption on the Lipid Profile of Female Soccer Players

“…Singh investigated the effect of beetroot intake on the lipid profile of active individuals. They reported that beetroot juice reduced triglyceride, cholesterol, and LDL while increasing HDL levels, which is in line with the current results (18). Kumar examined the anti-lipid activity of various beetroot extracts in mice.…”