Beet (Beta vulgaris) and Leek (Allium porrum) Leaves as a Source of Bioactive Compounds with Anti-quorum Sensing and Anti-biofilm Activity

Chemical Characterization and Antibiofilm Activities of Bulbs and Leaves of Two Aglione (Allium ampeloprasum var. holmense Asch. et Graebn.) Landraces Grown in Southern Italy

“…Then, the bacterial adhesion to surface becomes irreversible and the cells begin to secrete exopolysaccharides that decrease the amount of antimicrobial available to interact with biofilm [ 27 ]. Our results ascertained the potential use of the extracts of A. ampeloprasum that in our experiments resulted also much more effective than those obtained from A. porrum [ 11 ] or A. sativum [ 28 ] in inhibiting the formation of biofilm, although the times considered for the biofilm formation were different. Furthermore, they confirmed once again the enormous role that the vegetal extracts can exhibit in fighting not only to act ab origine on the adhesion of cells, preclude of biofilm formation, but also in exerting some mechanisms capable to affect the surface of bacterial cells or inside them, once the biofilm has formed (in our case, considering 24-h of preformed biofilms) and the microbial cells are trapped in [ 25 , 28 , 29 ].…”

“…The gap between the content of TPs in the aerial parts and bulbs of 'Irsina' not was so marked, although TPs content of the aerial parts resulted higher than that of the bulbs (5.266 mg/g of air-dried product and 4.438 mg/g of air-dried product, respectively). The presence of a high amount of total polyphenols in the leaves of Allium species has been reported also by Pellegrini and Ponce [11], who found 262.66 mg of total polyphenols in 100 g of the leaves of dried leek. The content we found proved inferior to that reported by Lu and co-workers [3] for bulbs and cloves of A. ampeloprasum.…”

“…The content we found proved inferior to that reported by Lu and co-workers [ 3 ] for bulbs and cloves of A. ampeloprasum . However, as is well known, the amount of secondary metabolites is affected by several factors, including the variety, the method of extraction, the harvesting time [ 11 ]. High levels of polyphenols have been reported also by Ceccanti and co-workers [ 8 ] for bulbs of of A. ampeloprasum var.…”

“…holmense to inhibit the growth of bacteria and to avoid or limit the adhesion capacity of bacteria and the following biofilm formation by bacteria and affect the metabolism of the cells present into the bacterial biofilm, which versatile scenario takes also place to the differences occurring in the susceptibility of planktonic and biofilm bacterial cells to antimicrobial agents. Pellegrini and Ponce [ 11 ] studied the antibacterial activity of the aerial parts extracts of Allium porrum , mainly related to their quorum quenching capacity and biofilm inhibitory action, and found that these extracts were capable to inhibit the bacterial biofilm of Escherichia coli ATCC 25158 at a concentration of 268.75 mg/mL. Therefore, the present study was carried out to determine the total polyphenol content of the extracts recovered by bulbs and aerial parts (these last often considered as by-products) of two landraces of A. ampeloprasum var.…”

Investigating Ghanaian Allium Species for Anti-Infective and Resistance-Reversal Natural Product Leads to Mitigate Multidrug-Resistance in Tuberculosis

“…For example, the biofilm inhibition properties of A. sativum, A. stipitatum , A . orientale and A. porrum have been documented [ 19 , 20 , 21 , 22 ]. The inhibition of bacterial efflux pumps has also been suggested as a strategy to inhibit biofilm formation [ 23 ].…”