Foot-and-mouth disease (FMD) is an infectious disease affecting pigs. The control of FMD in
swine husbandry is very important because its outbreak results in a vast economic loss. FMD
vaccination has effectively controlled FMD; however, it results in economic loss associated
with the incidence of lesions in the pork meat at the injection site. The objective of this
study was to investigate the effects of transdermal needle-free injection (NFI) of the FMD
vaccine on the incidence of lesions at the injection site. Pigs (n=493) in the control group
were vaccinated with the FMD vaccine using a commercial syringe needle, while 492 pigs in the
transdermal NFI group received the FMD vaccine using a needle-free gas-powered jet injector.
After the slaughter of the pigs, the incidence of lesions at the injection site of all pigs was
checked by plant workers. The result of this study showed that the incidence of lesions in the
pork ham from pigs vaccinated with NFI was 14.82% lower than that in control pigs
(p<0.01). In addition, lesions generated in the NFI group were found just in the
subcutaneous tissue. Therefore, the incidence of lesions at the injection site in pork from
pigs vaccinated with the FMD vaccine can be effectively reduced by using transdermal NFI rather
than a conventional syringe needle.