Bee venom acupuncture point injection for central post stroke pain: A preliminary single-blind randomized controlled trial

Cho, Seung‐Yeon; Park, Jooyoung; Jung, Woo-Sang; Moon, Sang-Kwan; Park, Jung-Mi; Ko, Chang-Nam; Park, Seong-Uk

doi:10.1016/j.ctim.2013.02.001

Cited by 35 publications

(30 citation statements)

References 10 publications

(12 reference statements)

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“…Our patient exhibited sensitive points around the Gall Bladder and Stomach meridians of the leg and they contributed to the treatment. It is in parallel with the "seven points for stroke" theory [7,17] of Korean Medicine, suggesting that oligodendroglioma has a similar mechanism as stroke in acupuncture treatment. Thus, our acupuncture at sensitive points is thought to be reasonable and to have played a role.…”

Section: Discussionmentioning

confidence: 84%

“…Recently, bee venom pharmacopuncture proved to even suppress the adverse effect of anti-cancer medication [22], and ameliorate brain diseases [7,8]. Therefore, bee venom pharmacopuncture at GV20 seems to have produced antiinflammatory and anti-cancer effects.…”

Section: Discussionmentioning

confidence: 98%

“…An increasing number of research articles show the interest in pharmacopuncture [4,5]. Especially, mountain ginseng pharmacopuncture is often used for cancer treatments, and bee venom pharmacopuncture is also used for cancer [6] as well as brain diseases [7,8], owing to its anti-inflammatory effects.…”

Section: Introductionmentioning

confidence: 99%

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Recurrent Oligodendroglioma Treated with Acupuncture and Pharmacopuncture

Lee

2015

Journal of Acupuncture and Meridian Studies

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Acupuncture and pharmacopuncture have been shown to be effective in tumor treatment. However, their effectiveness for treating oligodendroglioma has not been reported yet. The purpose of this study was to provide an initial report on the effectiveness of acupuncture and pharmacopuncture for the treatment of an oligodendroglioma by presenting a case that was treated successfully. A 54-year-old man, who had experienced intracranial hemorrhage, was diagnosed with recurrent oligodendroglioma. His expected survival period was 3-6 months. The patient received daily acupuncture and weekly pharmacopuncture of mountain ginseng and bee venom. After treatment for 18 months, the tumor size was decreased markedly on brain magnetic resonance imaging, and severe seizures had disappeared. In this case, a combination of acupuncture and pharmacopuncture was shown to be effective for the treatment of recurrent oligodendroglioma.

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Section: Discussionmentioning

confidence: 84%

Section: Discussionmentioning

confidence: 98%

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Recurrent Oligodendroglioma Treated with Acupuncture and Pharmacopuncture

Lee

2015

Journal of Acupuncture and Meridian Studies

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“…After reviewing the full texts, we deemed 8 English language studies that enrolled 459 patients with CPSP eligible for our review (Table 1). [37][38][39][40][41][42][43][44] There was almost perfect agreement (Φ=0.82) between reviewers at the full-text review stage. All trials evaluated treatment effects on pain, and none reported effects on physical functioning, role functioning, or interpersonal functioning (Figure 2).…”

Section: Resultsmentioning

confidence: 99%

“…44 Very low certainty evidence (Table V in the online-only Data Supplement) from another study (n=60) found no significant effect of electroacupuncture versus carbamazepine on a composite measure of joint pain, dysfunction, and tenderness. 39 …”

mentioning

confidence: 99%

Management of Central Poststroke Pain

Mulla

Wang

Khokhar

et al. 2015

Stroke

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C entral poststroke pain (CPSP) is a chronic (≥3 months) neuropathic disorder that can occur after a lesion or disease affecting the central somatosensory system. 1 The pain may be spontaneous, occurring either constantly or intermittently, or evoked in response to external stimuli.1 It may develop immediately after a stroke, or years later. [2][3][4][5] To date, the largest prospective study, which enrolled 15 754 participants with ischemic stroke from 35 countries, found that 2.7% of patients developed CPSP at 1 year after stroke.6 Because CPSP case definition is complex, 1 however, its reported prevalence is variable, and dependent on the site of lesion: 1 study, for instance, found that 25% of patients with brain stem infarcts developed CPSP within 6 months. 4 Individuals with CPSP commonly experience sensory abnormalities, including increased tactile and thermal sensitivities, which impair their quality of life. [7][8][9] The underlying mechanisms of CPSP are poorly understood, 1 contributing to challenges in its management.There are several pharmacological and nonpharmacological therapies available for patients with CPSP; few systematic Background and Purpose-Central poststroke pain is a chronic neuropathic disorder that follows a stroke. Current research on its management is limited, and no review has evaluated all therapies for central poststroke pain. Methods-We conducted a systematic review of randomized controlled trials to evaluate therapies for central poststroke pain. We identified eligible trials, in any language, by systematic searches of AMED, CENTRAL, CINAHL, DARE, EMBASE, HealthSTAR, MEDLINE, and PsychINFO. Eligible trials (1) enrolled ≥10 patients with central poststroke pain; (2) randomly assigned them to an active therapy or a control arm; and (3) collected outcome data ≥14 days after treatment. Pairs of reviewers, independently and in duplicate, screened titles and abstracts of identified citations, reviewed full texts of potentially eligible trials, and extracted information from eligible studies. We used a modified Cochrane tool to evaluate risk of bias of eligible studies, and collected patient-important outcomes according to recommendations by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials. We conducted, when possible, random effects meta-analyses, and evaluated our certainty in treatment effects using the Grading of Recommendations Assessment, Development, and Evaluation System. Results-Eight eligible English language randomized controlled trials (459 patients) tested anticonvulsants, an antidepressant, an opioid antagonist, repetitive transcranial magnetic stimulation, and acupuncture. Results suggested that all therapies had little to no effect on pain and other patient-important outcomes. Our certainty in the treatment estimates ranged from very low to low. Conclusions-Our

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Central Nervous System Pain

Salahuddin

Gebreyohanns

2020

Pain Management for Clinicians

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Bee venom acupuncture point injection for central post stroke pain: A preliminary single-blind randomized controlled trial

Cited by 35 publications

References 10 publications

Recurrent Oligodendroglioma Treated with Acupuncture and Pharmacopuncture

Recurrent Oligodendroglioma Treated with Acupuncture and Pharmacopuncture

Management of Central Poststroke Pain

Central Nervous System Pain

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