Bee Products in Dermatology and Skin Care

Kurek-Górecka, Anna; Górecki, Michał; Rzepecka‐Stojko, Anna; Balwierz, Radosław; Stojko, Jerzy

doi:10.3390/molecules25030556

Cited by 148 publications

(122 citation statements)

References 78 publications

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“…7,8 That being said, all types of propolis possess antimicrobial, anti-neoplastic, anti-inflammatory, antioxidant, hepatoprotective, cariostatic, and immunostimulatory activity. 8…”

Section: Propolis: Ancient Remedymentioning

confidence: 99%

Back to the basics: Propolis and COVID ‐19

Bachevski

Damevska

Simeonovski

et al. 2020

Dermatologic Therapy

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The epidemiological burden of COVID‐19 is a healthcare challenge throughout the world, not only in terms of testing the limits of medical capacities, but also as an enigma considering preventive strategies and methods. The upper respiratory tract mucosa is the first line of defense, as a physical barrier, as well as through multiple innate and adaptive immune mechanisms which are crucial for efficient antiviral responses. Identifying methods able to reduce or prevent colonization, viral adhesion, and promote virus shedding on mucous membranes or have the ability to inactivate pathogens and thus reduce virus dose and/or increase immune response would be essential in the management of COVID‐19 outbreak and help in flattening the curve. We review the effects of propolis, an old remedy with proven antiviral properties, as a possible low‐cost inhibitor of SARS‐CoV‐2 in the oropharyngeal niche, prophylaxis, or adjuvant therapy.

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“…7,8 That being said, all types of propolis possess antimicrobial, anti-neoplastic, anti-inflammatory, antioxidant, hepatoprotective, cariostatic, and immunostimulatory activity. 8…”

Section: Propolis: Ancient Remedymentioning

confidence: 99%

Back to the basics: Propolis and COVID ‐19

Bachevski

Damevska

Simeonovski

et al. 2020

Dermatologic Therapy

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“…This property is especially relevant for the applications of natural compounds in the development of biomaterials that promote wound healing. Bee products are used in the production of cosmetics and the development of drugs and can cause allergic reactions [ 19 ]. Dermatitis and contact allergy problems have also been reported in vitro [ 20 ] and for beekeepers and propolis consumers [ 21 ], which emphasizes the importance of assessing the allergenic properties of hydroalcoholic extracts of red propolis (RPE) [ 22 , 23 , 24 ], on account of their chemical composition.…”

Section: Introductionmentioning

confidence: 99%

New Insights for Red Propolis of Alagoas—Chemical Constituents, Topical Membrane Formulations and Their Physicochemical and Biological Properties

Silva

Basílio

et al. 2020

Molecules

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The main objectives of this study were to evaluate the chemical constitution and allergenic potential of red propolis extract (RPE). They were evaluated, using high performance liquid chromatography (HPLC) and the release of β-hexosaminidase, respectively. A plethora of biologically active polyphenols and the absence of allergic responses were evinced. RPE inhibited the release of β-hexosaminidase, suggesting that the extract does not stimulate allergic responses. Additionally, the physicochemical properties and antibacterial activity of hydrogel membranes loaded with RPE were analyzed. Bio-polymeric hydrogel membranes (M) were obtained using 5% carboxymethylcellulose (M1 and M2), 1.0% of citric acid (M3) and 10% RPE (for all). Their characterization was performed using thermal analysis, Fourier transform infrared (FTIR), total phenolic content, phenol release test and, antioxidant activity through 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) and Ferric Reducing Antioxidant Power (FRAP). The latter appointed to the similar antioxidant capacity of the M1, M2 and M3. The degradation profiles showed higher thermostability to M3, followed by M2 and M1. The incorporation of RPE into the matrices and the crosslinking of M3 were evinced by FTIR. There were differences in the release of phenolic compounds, with a higher release related to M1 and lower in the strongly crosslinked M3. The degradation profiles showed higher thermostability to M3, followed by M2 and M1. The antibacterial activity of the membranes was determined using the disc diffusion assay, in comparison with controls, obtained in the same way, without RPE. The membranes elicited antibacterial activity against Staphylococcus aureus and Staphylococcus epidermidis, with superior performance over M3. The hydrogel membranes loaded with RPE promote a physical barrier against bacterial skin infections and may be applied in the wound healing process.

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“…Apart from inhibition of microbes responsible for wound infections, honey has been shown to inhibit the growth of dermatophyte, Candida albicans and Propionibacterium acnes. 11,12 Turmeric, a commonly used Indian condiment, has been found to contain Curcumin which has anti-inflammatory, anti-oxidant, antimicrobial, anti-viral, wound healing, chemopreventive, chemosensitising, and radiosensitising properties and is commonly used for skin lightening and wound healing in traditional Indian medicine. 13,14 Fuller's earth (Mul- Even though the traditional home remedies are useful, but many products can have various adverse effects also.…”

Section: Discussionmentioning

confidence: 99%

“…Honey is another product which is commonly used and has been found to possess skin healing properties which have been attributed to its antimicrobial properties, its ability to modulate the skin's immune system and promote tissue repair. Apart from inhibition of microbes responsible for wound infections, honey has been shown to inhibit the growth of dermatophyte, Candida albicans and Propionibacterium acnes 11,12 . Turmeric, a commonly used Indian condiment, has been found to contain Curcumin which has anti‐inflammatory, anti‐oxidant, antimicrobial, anti‐viral, wound healing, chemopreventive, chemosensitising, and radiosensitising properties and is commonly used for skin lightening and wound healing in traditional Indian medicine 13,14 .…”

Section: Discussionmentioning

confidence: 99%

Home remedies in different pediatric dermatoses: An observational study

Gupta¹,

Bhargava

2020

Dermatologic Therapy

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Traditional medicinal systems are widely practiced in the Indian subcontinent for a wide variety of diseases. We aimed to identify the various home remedies used by people to treat numerous pediatric dermatoses. It was an observational study carried out over 18 months in which 150 children attending our clinics were recruited. A detailed history regarding the various indigenous preparations used was taken from caregivers and noted in a proforma. A total of 150 children (M:F-89:61) aged between 4 months to 18 years were included. Atopic dermatitis and eczema (n = 28) were the most common dermatoses whereas the most common home remedies used for these either solo or in combination were coconut oil (13), olive oil (11), mustard oil (7), aloevera gel (6), ghee (6), curd (4), and honey (2). Acne was the second most common dermatoses (n = 22), products used for acne were Fuller's earth, aloevera gel, turmeric, gram flour, mustard oil, lime and sandalwood paste. Other dermatoses treated by indigenous products included impetigo and other bacterial infections, seborrheic dermatitis, dermatophytoses, verruca, molluscum, hypopigmentary disorders, etc. In Indian setup, home remedies are commonly used by the caregivers before visiting a dermatologist to treat various pediatric dermatoses.

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Bee Products in Dermatology and Skin Care

Cited by 148 publications

References 78 publications

Back to the basics: Propolis and COVID ‐19

Back to the basics: Propolis and COVID ‐19

New Insights for Red Propolis of Alagoas—Chemical Constituents, Topical Membrane Formulations and Their Physicochemical and Biological Properties

Home remedies in different pediatric dermatoses: An observational study

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