Bedside monitoring of patients with shock using a portable spatially-resolved near-infrared spectroscopy

Abstract

Clinical monitoring of shock mainly depends on blood-oxygenindices obtained from invasive blood sample tests. The central internal jugular central vein oxygenation level (ScvO 2 ) has been considered as a gold standard indicator for shock prediction. We developed a noninvasive spatially-resolved near-infrared spectroscopy (SR-NIRS) to measure tissue blood oxygen saturation (StO 2 ) surrounding the region of taking blood sample for the ScvO 2 test in 25 patients with shock. StO 2 values were found to be highly correlated (r = 0.84, p < 0.001) with ScvO 2 levels and the concordance coefficient of 0.80 is high. The results suggest the potential of noninvasive SR-NIRS for bedside shock monitoring.

Optimal hemoglobin extinction coefficient data set for near-infrared spectroscopy

“…All experiments were performed in a dark room. A customized CW-NIRS system [18,19], which consisted of a probe, a functional module and a computer, was employed to record light intensity variations during experiments. The probe included a LED source with three-wavelength (735, 805, and 850 nm) and a photosensitive detector.…”

Longtime driving induced cerebral hemodynamic elevation and behavior degradation as assessed by functional near‐infrared spectroscopy and a voluntary attention test

“…Our fNIRS device consists of a flexible form probe and a control module coupled with a computer (Figure A). The probe was fixed over the subject's forehead with a black adjustable strap (Figure B).…”

Near-Infrared Spectroscopy-based Detector in Application of Intensive Care Unit Clinics

“…The inevitable hemorrhage during surgery and traumatic injury induced shock was known as a fatal complication with ~50% in mortality [16]. The conventional clinical method to estimate shock severity was to measure blood sample oxygen indices in the central internal jugular central vein, which was abbreviated as ScvO2.…”

“…We acquired data from 12 patients one day after shock treatment. For comparison, we not only analyzed StO2, but also ScvO2 which was a golden standard indicator for shock prediction, by linear analysis and BlandAltman plot [16].…”

“…Then we reported the measurement algorithm for NIRS device to measure disease-sensitive hemodynamic parameters. After that, we reported some successful OPT101 embedded ICU-specific NIRS devices, including the one for early-diagnosis and therapeutic effect tracking of thrombus, noninvasive monitoring of shock patients' conditions, and the one for fatigue evaluation of long time working medical staffs [9,15,16,17]. Clinical experimental tests were carried out to fully test the reliabilities of these devices.…”