Becker muscular dystrophy and successful intervention with mechanical thrombectomy of right atrial clot‐in‐transit with pulmonary embolism

Abstract

Becker's muscular dystrophy (BMD) is a muscle disease with an X-linked inheritance and is caused by mutations in the gene that code for the protein dystrophin. BMD is associated with partially functional dystrophin in variable amounts. 1,2 Patients with BMD may present with cardiac complications, specifically cardiomyopathy. 3 These patients may also present with early right ventricular dysfunction and late-onset left ventricle complications. 3 Right heart thrombi (RHT) are thrombi that may be found in the right atrium (RA), right ventricle (RV), or proximal surrounding vasculature. These can feature different characteristics of being mobile or immobile. 4 They may also adhere to devices in the body such as pacemakers. 4 The association between the occurrence of right atrial (RA) clot in-transit with subsequent pulmonary embolism (PE) ranges from nearly 4% to 18%. 5 The mortality of cases without therapy is between 80% and 100%. 6 Inari developed the FlowTriever system and intended for the treatment of pulmonary embolism through the peripheral vasculature without thrombolytics, as well as treating clots in-transit in the right atrium. The device consists of a large lumen catheter and large bore syringe