“…Previously published measurements of HRQoL at 1, 3, 6, and 12 months have been reported in four randomized trials mainly including younger patients at lower risk [19][20][21][22][23]. Additionally, one study obtained data from 328 of 401 randomized patients using a post-test only design with a median follow-up at 3 years [24]. Different instruments such as EuroQOL-6, EuroQOL (original version), EuroQOL-5, SF-36, and the 16-item Quality of Life Scale-Norwegian were used, all showing that HRQoL improved in off-pump and on-pump groups over time, but there were no significant differences between the surgical groups regardless of the instruments used or the design of the study.…”