Bearbeitung von Spenderhornhäuten zu Transplantations- zwecken mittels Excimerlaser: Herstellung hochpräziser Transplantate — Fortschritte und Anwendungen

Homolka, Peter; Biowski, Robert; Husinsky, W.; Blaas, C.; Baumgartner, Isabella; Grabner, Günther

doi:10.1007/978-3-642-60306-8_80

Cited by 1 publication

(1 citation statement)

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“…As in figure 9, the graft was cut centrally to demonstrate the surface topology of the lathed area. Equidistant ablation radii in combination with the use of semicircular laser spots produce a rather rough, wave-like surface structure with a radial period equal to the stepping distance of the scanning system (Homolka et al 1998, Biowski et al 1997 (figure 10). This effect disappears completely when using OSLA.…”

Section: Experimental Verification Of the Algorithmmentioning

confidence: 99%

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Homolka¹,

Biowski²,

Kaminski³

et al. 1999

Phys. Med. Biol.

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Area laser lathing and trephination of donor corneas is used to produce different types of grafts for human transplantation. 193 nm (ArF excimer) laser radiation is used, since this is known to give a non-thermal laser-tissue interaction with a minimal zone of tissue damage. To guarantee the highest degree of flexibility concerning the overall shape of the grafts as well as their thickness profiles, we use a small (compared with the area to be ablated) scanning laser spot. For area lathing of the tissue we have developed a new ablation algorithm (optimized scanning laser ablation, OSLA) that can be applied to lathe and perforate any tissue--with concave (as in this application), convex or plane surface geometry--where surface precision and smoothness are key issues. Using OSLA with the Excimer Laser Corneal Shaping System (a tool for in vitro fabrication of all kinds of corneal transplants like donor buttons for keratoplasty, lamellar grafts for epikeratoplasty and refractive lenticules) enabled us to produce all types of corneal grafts with very high precision. This is considered to be a major improvement towards the production of refractive lenticules.

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Section: Experimental Verification Of the Algorithmmentioning

confidence: 99%