Beam orientation selection for intensity-modulated radiation therapy based on target equivalent uniform dose maximization

Das, Shiva K.; Cullip, T; Tracton, Gregg; Chang, S; Marks, Lawrence B.; Anscher, Mitchell S.; Rosenman, Julian G.

doi:10.1016/s0360-3016(02)03817-8

Cited by 64 publications

(33 citation statements)

References 27 publications

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“…In this case, tools are needed to evaluate treatment plans in 3D-CRT. 8 One way this can be used consists of converting dose-volume histograms (DVHs) to an equivalent uniform dose (EUD), 9 and then estimating the tumour control probability (TCP) and the normal tissue complication probability (NTCP). 10,11 The concept of EUD, introduced by Niemierko, 12 was originally defined as the absorbed dose, that is, if given uniformly, would lead to the same cell death as the actual non-uniform absorbed-dose distribution.…”

mentioning

confidence: 99%

Assessment and quantification of patient set-up errors in nasopharyngeal cancer patients and their biological and dosimetric impact in terms of generalized equivalent uniform dose (gEUD), tumour control probability (TCP) and normal tissue complication probability (NTCP)

Boughalia¹,

Marcié²,

Fellah³

et al. 2015

BJR

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confidence: 99%

Assessment and quantification of patient set-up errors in nasopharyngeal cancer patients and their biological and dosimetric impact in terms of generalized equivalent uniform dose (gEUD), tumour control probability (TCP) and normal tissue complication probability (NTCP)

Boughalia¹,

Marcié²,

Fellah³

et al. 2015

BJR

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“…For Hybrid-IMRT plan, manual beam selection is influenced by the nonintuitive dose contribution of each beam to the target and critical normal tissues. Selecting several beam angles by planners from a large number of beams with different orientations may increase quality assurance time, planning time, and treatment time [23]. In this study, the beam angles of the Hybrid-IMRT plan were initially optimized using the beam angle optimization (BAO) algorithm.…”

Section: Discussionmentioning

confidence: 99%

A Hybrid IMRT/VMAT Technique for the Treatment of Nasopharyngeal Cancer

Zhao

Yang

Jiang

et al. 2015

BioMed Research International

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Hybrid IMRT/VMAT technique which combined intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) was developed for the treatment of nasopharyngeal cancer (NPC). Two-full-arc VMAT (2ARC-VMAT), 9-field IMRT (9F-IMRT), and Hybrid IMRT/VMAT plans for NPC were compared in terms of the dosimetric quality, sparing of organs at risk (OARs), and delivery efficiency. The Hybrid IMRT/VMAT technique can improve the target dose homogeneity and conformity compared with 9F-IMRT and 2ARC-VMAT. It can reduce the dose delivered to the TMJ, mandible, temporal lobe, and unspecified tissue with fewer MUs compared with 9F-IMRT and dose delivered to parotids, brainstem, and spinal cord compared with 2ARC-VMAT technique. The mean delivery time of Hybrid plans was shorter than that of 9F-IMRT plans (408 s versus 812 s; P = 0.00) and longer than that of 2ARC-VMAT plans (408 s versus 179 s; P = 0.00). Hybrid IMRT/VMAT technique could be a viable radiotherapy technique with better plan quality.

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“…Scoring techniques are used in iterative beam selection approaches in Das et al (2003), Ehrgott and Johnston (2003), and Meedt et al (2003). Starting with an initial collection of p angles, A 0 , a score is used to find a subsequent collection of angles, A t .…”

Section: Local Searchmentioning

confidence: 99%

Mathematical optimization in intensity modulated radiation therapy

et al. 2009

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The design of an intensity modulated radiotherapy treatment includes the selection of beam angles (geometry problem), the computation of an intensity map for each selected beam angle (intensity problem), and finding a sequence of configurations of a multileaf collimator to deliver the treatment (realization problem). Until the end of the last century research on radiotherapy treatment design has been published almost exclusively in the medical physics literature. However, since then, the attention of researchers in mathematical optimization has been drawn to the area and important progress has been made. In this paper we survey the use of optimization models, methods, and theories in intensity modulated radiotherapy treatment design. This is an updated version of the paper that appeared in 4OR, 6(3), 199-262 (2008).

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Beam orientation selection for intensity-modulated radiation therapy based on target equivalent uniform dose maximization

Cited by 64 publications

References 27 publications

Assessment and quantification of patient set-up errors in nasopharyngeal cancer patients and their biological and dosimetric impact in terms of generalized equivalent uniform dose (gEUD), tumour control probability (TCP) and normal tissue complication probability (NTCP)

Assessment and quantification of patient set-up errors in nasopharyngeal cancer patients and their biological and dosimetric impact in terms of generalized equivalent uniform dose (gEUD), tumour control probability (TCP) and normal tissue complication probability (NTCP)

A Hybrid IMRT/VMAT Technique for the Treatment of Nasopharyngeal Cancer

Mathematical optimization in intensity modulated radiation therapy

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