2008
DOI: 10.1038/nrn2298
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Be smart, exercise your heart: exercise effects on brain and cognition

Abstract: An emerging body of multidisciplinary literature has documented the beneficial influence of physical activity engendered through aerobic exercise on selective aspects of brain function. Human and non-human animal studies have shown that aerobic exercise can improve a number of aspects of cognition and performance. Lack of physical activity, particularly among children in the developed world, is one of the major causes of obesity. Exercise might not only help to improve their physical health, but might also imp… Show more

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Cited by 2,669 publications
(2,184 citation statements)
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References 85 publications
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“…17 Furthermore, interventional studies have reported a volume increase in the hippocampus as a beneficial result of physical exercise 5 in contrast to our findings here. However, the study by Erickson et al 5 reported-despite the overall increase-a wide range of volumetric changes in the hippocampus, indicating both increases and decreases of the hippocampal volume in participants after long-lasting aerobic exercise.…”
Section: Structural Resultscontrasting
confidence: 95%
“…17 Furthermore, interventional studies have reported a volume increase in the hippocampus as a beneficial result of physical exercise 5 in contrast to our findings here. However, the study by Erickson et al 5 reported-despite the overall increase-a wide range of volumetric changes in the hippocampus, indicating both increases and decreases of the hippocampal volume in participants after long-lasting aerobic exercise.…”
Section: Structural Resultscontrasting
confidence: 95%
“…Drugs may seem distinctive among enhancements in that they bring about their effects by altering brain function, but in reality so does any intervention that enhances cognition. Recent research has identified beneficial neural changes engendered by exercise 10 , nutrition 11 and sleep 12 , as well as instruction 13 and reading 14 . In short, cognitive-enhancing drugs seem morally equivalent to other, more familiar, enhancements.…”
Section: Favouring Innovationmentioning
confidence: 99%
“…It is possible that this is due to the established relations of cognitive ability with health behaviors: for instance, individuals with better cognitive ability tend to smoke less and exercise more (Gottfredson, 2004), and these lifestyle factors may impact brain structure (e.g. [Almeida et al, 2011; Hillman et al, 2008]; note that such factors were not measured in this study). There were, however, no significant associations in the opposite direction: broad measures of brain size, either total volume or specific volumes of grey matter, white matter, or WMH, did not serve as an early indicator of impending cognitive decline, despite in some cases predicting more volume loss.…”
Section: Discussionmentioning
confidence: 98%