Abstract:Persistent organic pollutants (POPs) may alter tumor cells phenotype, possibly increasing malignancy, but
there is a lack of studies investigating the mechanisms by which POPs may affect tumor cells. The ATP-Binding Cassette (ABC) transporter proteins are a widely studied component of drug resistance and tumor
progression. We hypothesized that the levels of BDE-209 and TCDD detected in human serum can modulate
the gene expression or activity of ATP-binding cassette (ABC) transporters in murine melanoma (B16… Show more
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