BCG Site Reactivation in Kawasaki Disease

Kumar, Ankur; Singh, Surjit

doi:10.1002/art.39708

Cited by 8 publications

(5 citation statements)

References 4 publications

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“…Similarly, reactivation of the bacillus Calmette-Gu erin (BCG) injection site is a pathognomonic clinical sign of KD and may be more commonly observed than cervical lymphadenopathy. 21,22 However, this has not been given enough consideration in the diagnostic criteria. Sterile pyuria, 23 peripheral arthritis, 24 hydrops of gall bladder 25 and myocarditis 4,26 are other important indicators of KD.…”

Section: Clinical Signs With Diagnostic Importance But Not Included Imentioning

confidence: 99%

Diagnosis of Kawasaki disease

2017

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Kawasaki disease (KD) is a medium vessel vasculitis with predilection for coronary arteries. Due to lack of a reliable confirmatory laboratory test, the diagnosis of KD is based on a constellation of clinical findings that appear in a typical temporal sequence. These diagnostic criteria have been modified from time to time and the most recent guidelines have been proposed by the American Heart Association (AHA) in 2017. However, several children may have incomplete or atypical forms of KD and the diagnosis can often be difficult, especially in infants and young children. In this review, we have detailed the steps involved in arriving at a diagnosis of KD and also highlight the important role of echocardiography in diagnosis and management of children with KD.

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Section: Clinical Signs With Diagnostic Importance But Not Included Imentioning

confidence: 99%

Diagnosis of Kawasaki disease

2017

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“…Arthritis in KD is typically oligoarthritis, involving large joints and resolves without sequelae [31]. Erythema at BCG injection site is an important clinical sign during acute stage of KD and more common in infants [32]. Hydrops of gall bladder is also an important finding during acute stage.…”

Section: Changes In Lips and Oral Cavitymentioning

confidence: 99%

Kawasaki Disease

Pilania¹,

Singh²

2019

Periodic and Non-Periodic Fevers

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Kawasaki disease (KD) is an acute and usually self-limiting medium vessel vasculitis of childhood that has a predilection to involve the coronary arteries. It is characterized by the sequential appearance of a constellation of clinical features [1]. However, none of these clinical findings is, in itself, pathognomonic of KD. Many of these clinical features can, in fact, be seen in other common febrile illnesses of children. It is for this reason that the diagnosis of KD is often considered to be a clinical challenge [2]. Approximately 15-25% of untreated patients may go on develop coronary artery abnormalities (CAAs) and this remains the major cause of morbidity, and occasional mortality, in KD [3].

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“…All paediatricians need to be familiar with some of the pathognomonic clinical findings of KD that are not emphasized in the American Heart Association (AHA) diagnostic criteria 30 . These include reactivation of the Bacillus Calmette–Guérin (BCG) injection site 29 , sterile pyuria 31,32 , perineal peeling, arthritis, myocarditis, and hydrops of gall bladder.…”

Section: The Dilemma Of ‘Incomplete’ and ‘Atypical’ Kdmentioning

confidence: 99%

The emergence of Kawasaki disease in India and China

Jiao

Jindal

Vignesh

et al. 2018

gcsp

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Kawasaki disease (KD) is recognized as a leading cause of acquired heart disease in children in developed countries. Although global in distribution, Japan records the highest incidence of KD in the world. Epidemiological reports from the two most populous countries in the world, namely China and India, indicate that KD is now being increasingly recognized. Whether this increased reporting is due to increased ascertainment, or is due to a true increase in incidence, remains a matter of conjecture. The diagnosis and management of KD in developing countries is a challenging proposition. In this review we highlight some of the difficulties faced by physicians in managing children with KD in resource-constrained settings.

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BCG Site Reactivation in Kawasaki Disease

Cited by 8 publications

References 4 publications

Diagnosis of Kawasaki disease

Diagnosis of Kawasaki disease

Kawasaki Disease

The emergence of Kawasaki disease in India and China

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