Bazex paraneoplastic acrokeratosis in prostate carcinoma

Obasi, O. E.; Garg, Shveta

doi:10.1111/j.1365-2133.1987.tb07498.x

Cited by 34 publications

(18 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Acrokeratosis paraneoplastica Bazex can appear in patients with genitourinary tumours, such as prostate cancer and bladder cancer, too . It has been described in patients with Hodgkin disease and other lymphomas, such as T‐cell lymphomas or multiple myeloma as well as in neuroendocrine tumours .…”

Section: Resultsmentioning

confidence: 99%

Acrokeratosis paraneoplastica (Bazex syndrome) – a systematic review on risk factors, diagnosis, prognosis and management

Räßler

Goetze

Elsner

2017

Acad Dermatol Venereol

View full text Add to dashboard Cite

Acrokeratosis paraneoplastica Bazex (Bazex syndrome) is a rare paraneoplastic skin disease defined by erythematous, violaceous, scaly plaques on the hands and feet and on other acral locations such as nose and ears. Bazex syndrome is linked to a variety of underlying malignancies. Usually the skin lesions develop prior to the diagnosis of an internal malignant neoplasm with spontaneous remission after tumour removal. The objective of this study was to review the so far reported risk factors, diagnostic work-up, prognosis and treatment options for Bazex syndrome in a systematic manner. This systematic review is based on a search in MEDLINE, EMBASE and Cochrane Central Register for English and German articles from 1990 to 2015. Evidence on the diagnosis and treatment of Bazex syndrome is limited predominately to case reports or to small case series. There are no randomized controlled trials. A number of underlying tumour entities, predominately oropharyngeal neoplasms and tumours of the gastroenterological tract, but other malignancies were reported. Treatment modalities including topical and systemic corticosteroids, salicylic acid, topical vitamin D analogues, etretinate and PUVA therapy are often ineffective. Due to the small number of patients and the frequent misdiagnosis of this clinical entity, the aim of this systematic review was to call attention to this rare condition and to help clinicians to diagnose and treat Bazex syndrome effectively. Because of the good prognosis of the skin lesions and the tendency to resolve spontaneously if the underlying tumour is treated early, the differential diagnosis of Bazex syndrome should be taken into consideration when dealing with atypical psoriasiform cutaneous lesions. An early diagnosis may improve the patient's prognosis substantially.

show abstract

Section: Resultsmentioning

confidence: 99%

Acrokeratosis paraneoplastica (Bazex syndrome) – a systematic review on risk factors, diagnosis, prognosis and management

Räßler

Goetze

Elsner

2017

Acad Dermatol Venereol

View full text Add to dashboard Cite

show abstract

“…Additional or deviating forms and sites of skin lesions have been reported. These descriptions include erythrodermia [49,61], lichenification [71,73,87], acrocyanosis [15,51,55,81,91], periungual erythematous swelling [18,47,87,93] and complete onychoatrophy [13,17,19,23,27]. Bullous skin lesions have been described [15,19,30,40,56], as well as vesicles [51,68,87] and pustules [31,92].…”

Section: Evolution Of Skin Lesionsmentioning

confidence: 97%

“…In general, cutaneous lesions preceded tumor symptoms or diagnosis for an average period of 2-6 months. Longer periods were involved in some cases, ranging from 1 year to 6 years [14,32,33,55,61,71,75,86]. There have been a few cases, in which skin lesions developed after treatment for a malignancy.…”

Section: Evolution Of Skin Lesionsmentioning

confidence: 97%

Bazex syndrome (acrokeratosis paraneoplastica)

Sarkar

Knecht

Sarkar

et al. 1998

European Archives of Oto-Rhino-Laryngology

View full text Add to dashboard Cite

Acrokeratosis paraneoplastica (Bazex syndrome) is a rare but distinctive dermatosis associated with carcinomas of the upper aerodigestive tract with possible cervical lymph node metastases. The cutaneous lesions occurring in the syndrome are non-metastatic skin involvement that parallels (as cutaneous marker) the evolution of the malignancy. Since only a few case reports have been published in the otolaryngologic literature, we present our experience and review some of the findings previously reported.

show abstract

“…Other prostate cancer-associated dermatoses that have been recognized include the following: Bazex syndrome, [68,69] sign of Leser-Trelat, ichthyosis acquisita [69], erythroderma [70], and eruptive nevi [71].…”

Section: Paraneoplastic Dermatoses Of Prostate Cancermentioning

confidence: 98%

Skin Manifestations of Internal Disease in Older Adults

Markus¹,

Perry²,

Lear³

2015

Curr Geri Rep

View full text Add to dashboard Cite

The skin is the largest and most visible organ in the body and can give diagnostic clues of systemic illness. These clues often become obscured through the normal aging process. The purpose of this review is to give an overview of the normal skin changes seen with aging and then discuss new findings with regards to cutaneous signs of systemic disease in the elderly. We performed a literature search on cutaneous manifestations of internal disease and limited our search to articles published within the last 5 years. We then narrowed down the articles on conditions that primarily affect the adults over the age of 65; conditions commonly seen in the elderly as well as new findings which we felt were of great significance. Ultimately, we hope to update the reader on new cutaneous diagnostic tools of internal disease.

show abstract

Bazex paraneoplastic acrokeratosis in prostate carcinoma

Cited by 34 publications

References 2 publications

Acrokeratosis paraneoplastica (Bazex syndrome) – a systematic review on risk factors, diagnosis, prognosis and management

Acrokeratosis paraneoplastica (Bazex syndrome) – a systematic review on risk factors, diagnosis, prognosis and management

Bazex syndrome (acrokeratosis paraneoplastica)

Skin Manifestations of Internal Disease in Older Adults

Contact Info

Product

Resources

About