Bayesian estimation of the true prevalence of Mycobacterium avium subsp. paratuberculosis infection in Cypriot dairy sheep and goat flocks

Liapi, Maria; Leontides, Leonidas; Kostoulas, Polychronis; Botsaris, George; Iacovou, Y.; Rees, Catherine; Georgiou, K.; Smith, Graham C.; Naseby, D.C.

doi:10.1016/j.smallrumres.2010.09.010

Cited by 23 publications

(26 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We found fifteen herds which included 275 individuals to be seropositive and accordingly the average estimate of within-herd true prevalence was calculated as 14.6% in this study (Table 1). These findings are similar to reports from Germany (21%; Stau et al 2012) and Cyprus (24.6%; Liapi et al 2011). The possible within herd transmission could occur by continuous new Map infection in adult animals and high seroprevalence with eventual contamination of the environment.…”

Section: Discussionsupporting

confidence: 89%

See 1 more Smart Citation

Estimated apparent and true prevalences of paratuberculosis in sheep herds of the Kars Region in Northeastern Turkey

Büyük¹,

Çelebi²,

Akça³

et al. 2014

Vet. Med.

View full text Add to dashboard Cite

Paratuberculosis, caused by Mycobacterium avium subsp. paratuberculosis (Map), is one of the most prevalent and costly infectious diseases of livestock, particularly sheep and cattle herds. The aim of this study was to estimate true animal, within-herd, and between-herd prevalence of Map antibodies in sheep herds of the Kars Region in the Northeast part of Turkey. A seroprevalence study was carried out using a commercial ELISA kit. Twenty six sheep herds, non-vaccinated against Map, were randomly selected in different regions and in total 450 sheep aged 24 months and more were sampled. Herds were declared positive if one or more sheep in the herd tested positive for Map antibodies. The animal, within-herd, and between-herd apparent prevalences were calculated as 6.2% (95% CI = 4.3 to 8.8%), 10.2% (95 CI = 7.1 to 14.3%) and 57.7% (95% CI = 38.9 to 74.5%), respectively. True prevalences were estimated by conversion from apparent prevalences via the Rogan-Gladen estimator. True animal, within-herd, and between-herd prevalences were calculated as 8.3% (95% CI = 4.7 to 11.8), 14.6% (95 CI = 8.9 to 20.2) and 90% (95 CI = 59.8 to 120.1), respectively. The results provide useful information regarding the prevalence of Map infection in sheep herds in the Kars Region and will hopefully attract the special attention of veterinarians and promote the establishment of an efficient control programme.

show abstract

Section: Discussionsupporting

confidence: 89%

“…The true individual prevalence was estimated to be 8.3% in the Kars Region (Table 1). The animal-level prevalence rate calculated here is similar to those reported in studies conducted worldwide in small ruminants; especially in sheep (Coelho et al 2007;Liapi et al 2011;Stau et al 2012).…”

Section: Discussionsupporting

confidence: 86%

Estimated apparent and true prevalences of paratuberculosis in sheep herds of the Kars Region in Northeastern Turkey

Büyük¹,

Çelebi²,

Akça³

et al. 2014

Vet. Med.

View full text Add to dashboard Cite

show abstract

“…Previously, it was observed that antibodies against paratuberculosis were not related with histopathological lesions to detect infected sheep with focal lesions which had small numbers of acid-fast bacilli (Hope et al, 2000). Although the sensitivity of the ELISA technique used in the current study was quite similar as reported by Liapi et al, (2011), the lower sensitivity observed, when used as unique diagnosis technique, could be associated to differences in the stage of the disease that conditioned the immunological response of the animal. Previous studies indicated that both faecal microscopy and ELISA could be adopted to improve the diagnostic of paratuberculosis at field (Singh et al, 2009(Singh et al, , 2013(Singh et al, , 2014.…”

Section: Discussionmentioning

confidence: 43%

Detection of Mycobacterium avium subsp. paratuberculosis by several diagnostics techniques in clinical suspected sheep

Coelho

Coelho²,

García‐Díez

et al. 2018

J Hellenic Vet Med Soc

View full text Add to dashboard Cite

A total of thirty sheep with clinical symptomatology of paratuberculosis (Johne’s disease) were subjected to four diagnostic techniques: histopathological examination, bacteriological culture (in faeces and tissues), polymerase chain reaction (PCR) (in blood, tissue and faecal samples) and antibody responses (ELISA). Twenty-one (70.0%) animals showed histological lesions. Bacterial culture of both faeces and tissue revealed that 2 (6.7%) and 6 (20.0%) of the 30 sheep were infected, respectively. Mycobacterium avium subsp. 24 paratuberculosis (Map) was identified in 4 animals via PCR of faeces (13.3%), and in 19 (63.3%) by PCR in tissues. PCR in blood revealed 7 (23.3%) infected animals. Three (10.0%) animals showed antibodies against Map. A greater number of positive animals were detected by histopathological examination and PCR in tissues than by culture or ELISA. This study confirmed the clinical findings and results suggest that histopathology, PCR in tissues and in blood can improve the detection of Map in physically suspected animals and should be considered useful tools in the diagnosis of Map in suspected sheep.

show abstract

“…Prevalence of Johne's disease in goats has been reported from all over the world with prevalence of 7.9% in Republic of Cyprus (Liapi et al, 2011), 76.9% USA (Manning et al, 2002), 74.3%Chile (Salgado et al, 2007), 62.9% France (Mercier et al, 2010), 79.4 %India (Singh et al, 2013) and 44.1% Argentina (Fiorentino et al, 2012).…”

Section: Epidemiologymentioning

confidence: 99%

Epidemiology and Management Strategies of Johne's disease in Endemic Situations

Munir

Hassan

Muhammad³

et al. 2014

Res. j. vet. pract.

View full text Add to dashboard Cite

Mycobacterium paratuberculosis the subspecies of M. avium, effects wide range of animals including domestic cattle, sheep, goats, buffaloes, camelids and wild ruminants resulting in progressive and chronic enteritis known as Johne's disease (paratuberculosis). Clinically sick animals show emaciation, diarrhea and eventually death but the risk is that mostly they don't show clinical sign still can shed bacteria in feces and milk. Organism spread in the animal body through blood and lymph nodes to multiple internal organs. It is economically very important disease in livestock because effected livestock is recommended to be culled due to high treatment costs. Etiology, host range, immunology, epidemiology, stages/ forms, clinical signs, diagnostic tools and treatment have been discussed with special reference to endemic situations. Strategies to control this disease include improved management practices, testing and culling and vaccination. Modifications in management practices is not an easy job and so is the case with testing and culling; vaccine on the other hand is the simple practice but it is not usually practiced by farmers because lack of knowledge/awareness in herdsmen and availability of vaccine.All copyrights reserved to Nexus® academic publishers

show abstract

Bayesian estimation of the true prevalence of Mycobacterium avium subsp. paratuberculosis infection in Cypriot dairy sheep and goat flocks

Cited by 23 publications

References 22 publications

Estimated apparent and true prevalences of paratuberculosis in sheep herds of the Kars Region in Northeastern Turkey

Estimated apparent and true prevalences of paratuberculosis in sheep herds of the Kars Region in Northeastern Turkey

Detection of Mycobacterium avium subsp. paratuberculosis by several diagnostics techniques in clinical suspected sheep

Epidemiology and Management Strategies of Johne's disease in Endemic Situations

Contact Info

Product

Resources

About