“…With growing interest in the Poisson -Gaussian noise model, there exist many methods of image denoising of images under Poisson -Gaussian noise, for instance, the simplified noise model [Jeong et al, 2014], Variance Stabilization [Bohra et al, 2019], exact Poisson -Gaussian likelihood [Chouzenoux et al, 2015], blindspot neural network [Khademi et al, 2021], total variation (TV) based methods [Calatroni, De Los Reyes, Schronlieb, 2017], Anscombe transformation [Makitalo, Foi, 2013], dictionary learning [Zou, Xia, 2018] etc.…”