Basosquamous carcinoma masquerading as angiolymphoid hyperplasia

Aruna, Chintaginjala; Ramamurthy, D V S B; Kamcharla, Lakshmi

doi:10.4103/0019-5154.174184

Cited by 1 publication

(2 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Occasional co‐existence of ALHE with scabies infestation has also been reported . There is also an association of ALHE with SCC in which the removal of the tumor apparently induced regression of the ALHE, as well as a case of ALHE co‐existing with a basosquamous carcinoma . Additionally there are at least 2 cases in which the histopathologic pattern of ALHE mimicked an angiosarcoma, including an infiltration of the dermis by infiltrative blood vessels of varying sizes, lined by atypical endothelial cells …”

Section: Discussionmentioning

confidence: 98%

“…26 There is also an association of ALHE with SCC in which the removal of the tumor apparently induced regression of the ALHE, 27 as well as a case of ALHE co-existing with a basosquamous carcinoma. 28 Additionally there are at least 2 cases in which the histopathologic pattern of ALHE mimicked an angiosarcoma, including an infiltration of the dermis by infiltrative blood vessels of varying sizes, lined by atypical endothelial cells. 29,30 We have not found in the literature any previous examples of leukemia or syringocystadenoma papilliferum co-existing with ALHE.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Three unusual histopathological presentations of angiolymphoid hyperplasia with eosinophilia

Fernández-Flores

2017

J Cutan Pathol

View full text Add to dashboard Cite

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a poorly understood benign vasculoproliferative disorder. Histopathologically, the lesions are composed of a dermal or subcutaneous proliferation of blood vessels of varying sizes with plump and bland endothelial cells, which often show vacuolization and protrusion of the cytoplasm into the lumen. The vascular proliferation is admixed with a diffuse inflammatory infiltrate composed of lymphocytes, eosinophils and mast cells. Lymphoid follicles with germinal centers can sometimes be seen. In addition, fibrosis is a common accompanying feature. Some clinical and histopathological variants of ALHE have already been described in the literature. In this report, we present 3 rare associations of ALHE that have not been previously described. Case 1 was a 73-year-old woman with a lesion on her right medial thigh. Examination showed ALHE admixed with a chronic lymphocytic leukemic (CLL) infiltrate. Case 2 was a 55-year-old woman with a lesion on her right anterior ankle, which was a syringocystadenoma papilliferum co-existing with an ALHE. Case 3 was a 54-year-old man with a lesion on the left medial thigh, which showed overlapping features of IgG4-related disease associated with areas of ALHE. Given these multiple and diverse associations, it seems likely that ALHE may be a reactive rather than neoplastic process.

show abstract

Section: Discussionmentioning

confidence: 98%