Basics of Extracorporeal Membrane Oxygenation

Wrisinger, William C.; Thompson, Shaun

doi:10.1016/j.suc.2021.09.001

Cited by 19 publications

(20 citation statements)

References 48 publications

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“…Safe pressure within the circuit is usually 300 mmHg, wherein 600 mmHg incurs the risk of rupture. The membrane oxygenator's function is to provide a large surface area allowing for efficient gas exchange [39]. The effectiveness of the exchanger is measured as the amount of 75% saturated blood that can be further oxygenated to 95%.…”

Section: The Ecmo Ins and Outsmentioning

confidence: 99%

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Antibiotics and ECMO in the Adult Population—Persistent Challenges and Practical Guides

2022

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Extracorporeal membrane oxygenation (ECMO) is an emerging treatment modality associated with a high frequency of antibiotic use. However, several covariables emerge during ECMO implementation, potentially jeopardizing the success of antimicrobial therapy. These variables include but are not limited to: the increased volume of distribution, altered clearance, and adsorption into circuit components, in addition to complex interactions of antibiotics in critical care illness. Furthermore, ECMO complicates the assessment of antibiotic effectiveness as fever, or other signs may not be easily detected, the immunogenicity of the circuit affects procalcitonin levels and other inflammatory markers while disrupting the immune system. We provided a review of pharmacokinetics and pharmacodynamics during ECMO, emphasizing practical application and review of patient-, illness-, and ECMO hardware-related factors.

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Section: The Ecmo Ins and Outsmentioning

confidence: 99%

“…Carbon dioxide can be added for specific indications. The gas mixture is pumped through capillary tubing infused with blood, which flows counter to the gas [39]. Carbon dioxide exchange is quite efficient, while oxygen transfer is more limited due to the gases' respective water solubility.…”

Section: The Ecmo Ins and Outsmentioning

confidence: 99%

Antibiotics and ECMO in the Adult Population—Persistent Challenges and Practical Guides

2022

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“…11 Peripheral cannulation involves usually the right internal jugular vein or femoral vein for drainage with an arterial outflow cannula in the femoral artery being the most common. 12 VV ECMO is used for patients with a significant respiratory disease requiring removal of CO 2 and infusion of oxygen. Cannulation typically involves a drainage cannula in the femoral vein and a return cannula carrying oxygenated blood into an internal jugular vein (Fig.…”

Section: Ecmo Configurationsmentioning

confidence: 99%

Mechanical circulatory support in the intensive care unit

Sommer

Nunnally

2022

International Anesthesiology Clinics

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“…Extracorporeal membrane oxygenation (ECMO) is a life support technique that supports patients with heart and/or respiratory failure. [1][2][3] ECMO involves removing blood from a vein, expelling carbon dioxide through membrane pulmonary oxygenation, and then returning the oxygenated blood to the patient.…”

Section: Introductionmentioning

confidence: 99%

“…This technique was first successfully applied in adults in 1971 and has been used for more than 50 years. [1][2][3] Recently, indications for ECMO have expanded to include sepsis, poisoning, the resection of large airway neoplasms, and congenital diaphragmatic hernias in newborns. [4][5][6][7] ECMO can be classified into two types depending on the site of cannulation: venovenous (VV) ECMO, which provides only respiratory support, and venoarterial (VA) ECMO, which allows simultaneous cardiopulmonary support.…”

Section: Introductionmentioning

confidence: 99%