Basic science of dermoscopy

Ankad, Balachandra S; Smitha, SV; Koti, Varsha R

doi:10.4103/cdr.cdr_71_20

Cited by 7 publications

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“…Dermatologist then apply specific criteria and visual inspection techniques with the naked eye or dermoscopy ( Kato et al, 2019 ). Dermoscopy is a technique that uses cross-polarized light and a magnifier placed on skin covered with liquid to see structures in the epidermis and superficial dermis that are not visible to the naked eye, thus allowing for better recognition of the signs of melanoma ( Ankad et al, 2020 ). If the lesion requires additional investigation, an incisional (partial) or excisional (complete) biopsy is performed for histology, with excisional biopsy being the standard of care ( Shellenberger et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Circulating miRNAs as biomarkers for the diagnosis in patients with melanoma: systematic review and meta-analysis

Jones,

Nonaka

2024

Front. Genet.

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Objective: Melanoma is the most aggressive and deadly form of skin cancer, especially at later stages. There is currently no excellent diagnostic test established for the diagnosis of melanoma; however, circulating microRNAs (miRNAs) have shown some promise. We seek to conduct a systematic review and meta-analysis to establish the clinical utility of circulating miRNAs in diagnosing melanoma.Methods: PubMed, Wiley, and Web of Science were searched for studies that determined miRNA sensitivity and specificity in patients with melanoma. The included studies were assessed in Stata, and the sensitivity, specificity, summary receiver operating characteristic (SROC), positive likelihood ratio, negative likelihood ratio, and the area under the SROC curve (AUC) were calculated.Results: 9 studies with 898 melanoma patients were included in the meta-analysis. The circulating miRNAs showed high diagnostic accuracy with a sensitivity of 0.89 (p < 0.001), specificity of 0.85 (p < 0.001), diagnostic odds ratio of 45, and an area under the curve of 0.93.Conclusion: Circulating miRNAs have shown a high diagnostic power in detecting melanoma.

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Section: Introductionmentioning

confidence: 99%

Circulating miRNAs as biomarkers for the diagnosis in patients with melanoma: systematic review and meta-analysis

Jones,

Nonaka

2024

Front. Genet.

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A Compendium of Common Signs in Dermoscopy, Trichoscopy, and Onychoscopy

Bose

Khandare

Kulkarni³

et al. 2023

Clinical Dermatology Review

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Comparative Study of Trichoscopic Features of Alopecia Areata between Adults and Children and between Different Body Parts (Scalp, Beard, Eyebrow, and Moustache)

Raheem,

Al-Dhalimi

2024

Indian Journal of Dermatology

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Background: Round patches of baldness on the scalp or entire body are typically caused by the common, non-scarring hair loss condition known as alopecia areata (AA). Follicular units with two to four terminal hairs and one or two vellus hairs can be seen on a healthy, typical scalp trichoscopy. Aim of the Study: To compare trichoscopic features between adults and children and between different body parts. Patients and Methods: A cross-sectional observational study was performed on 90 patients; AA of the scalp and other body parts attended the dermatology out-patient clinic. A Gen Dermlite D100 Dermoscope was used to examine AA lesions and compare their features according to age and different body parts. Results: Scalp was the most common area among all patients, 65.6% (among adults, it was 50%, and among children, it was 85%), with a significant difference, P = 0.001. The most common trichoscopic feature among all patients was empty follicular opening in 74 (82.2%) lesions; among children, it was honeycomb pigment in 35 (87.5%) lesions, while among adults, it was empty follicular opening in 40 (80%) lesions. Tulip hair was significantly higher among adults, P = 0.036. At the same time, honeycomb pigment patterns and pohlpinkus constriction were significantly higher among children, P = 0.044 and P < 0.001, respectively. Conclusion: The most common trichoscopic feature of adult lesions was empty follicular opening, while honeycomb pigment was dominant among children. Tulip hair was higher among adults, while honeycomb pigment patterns and pohlpinkus constriction were higher among children.

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Basic science of dermoscopy

Cited by 7 publications

References 0 publications

Circulating miRNAs as biomarkers for the diagnosis in patients with melanoma: systematic review and meta-analysis

Circulating miRNAs as biomarkers for the diagnosis in patients with melanoma: systematic review and meta-analysis

A Compendium of Common Signs in Dermoscopy, Trichoscopy, and Onychoscopy

Comparative Study of Trichoscopic Features of Alopecia Areata between Adults and Children and between Different Body Parts (Scalp, Beard, Eyebrow, and Moustache)

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