In this paper we generalize the Jaynes-Cummings Hamiltonian by making use of some operators based on Lie algebras su(1,1) and su(2), and study a mathematical structure of Rabi floppings of these models in the strong coupling regime. We show that Rabi frequencies are given by matrix elements of generalized coherent operators (quant-ph/0202081) under the rotating-wave approximation.In the first half we make a general review of coherent operators and generalized coherent ones based on Lie algebras su(1,1) and su(2). In the latter half we carry out a detailed examination of Frasca (quant-ph/0111134) and generalize his method, and moreover present some related problems.We also apply our results to the construction of controlled unitary gates in Quantum Computation. Lastly we make a brief comment on application to Holonomic Quantum Computation. *