Basic knowledge of a microwave tissue coagulator and its clinical applications

Tabuse, Katsuyoshi

doi:10.1007/s005340050028

Cited by 70 publications

(59 citation statements)

References 13 publications

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“…In our study, postoperative fever was not significantly different between the two groups and it was only a low-grade fever, easily manageable with medical treatment. Compared to other tools used in liver surgery, the histopathological examination of the resected specimens from the microwave group revealed more prominent edge necrosis (6). Therefore, caution is advised when inserting the microwave needle, particularly when closing large vascular structures.…”

Section: Discussionmentioning

confidence: 87%

“…Successive punctures with a monopolar antenna create a continuous zone allowing hepatic dissection in the midline with reduced blood loss. The resonance of hydrogen and polar material from a microwave field heat tissue via mutual friction between hydrogen and hydrogen, polar material and its counterpart and hydrogen and polar material; subsequently, the antenna produces protein coagulation (6).…”

Section: Discussionmentioning

confidence: 99%

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Microwave tissue coagulation technique in anatomical liver resection

Tsuiki

Yin

et al. 2014

Biomedical Reports

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Abstract. Anatomical liver resection is currently the preferred treatment for liver cancer. With the recent introduction of medical microwave coagulation for liver metastases, anatomical hepatectomy may be performed more efficiently. The present study retrospectively reviewed the results of microwave tissue coagulation performed during anatomical liver resection for patients with liver disease at the TangDu Hospital (Xi'an, China) between January, 2009 and June, 2012. A total of 128 patients met the inclusion criteria and were divided into two groups for comparison; those treated with the microwave coagulation technique (n=66) and the conventional group (n=62), who were treated with standard partial hepatectomy. There was no reported perioperative mortality. The univariate analysis revealed that the duration of liver dissection, intraoperative blood loss, intraoperative erythrocyte transfusion volume and alanine aminotransferase levels on the 5th postoperative day were significantly different between the microwave and conventional groups (P<0.05). Therefore, microwave tissue coagulation in anatomical liver resection was shown to be efficacious and safe and, provided proficient skills are developed in this technique, microwave tissue coagulation may be an effective alternative to anatomical hepatectomy.

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Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Microwave tissue coagulation technique in anatomical liver resection

Tsuiki

Yin

et al. 2014

Biomedical Reports

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“…TACE reduces the hepatic blood flow and therefore the cooling effect by convection during the ablation process (19). Furthermore, ischemic and inflammatory effects of TACE therapy can induce edematous change in the tumor and peritumoral parts of the liver, and therefore may enlarge the coagulation area (8). In addition, microwave ablation acts directly on the center of the tumor, while TACE has more therapeutic effects on the greater vascularized periphery of the tumor.…”

Section: Discussionmentioning

confidence: 99%

“…Compared with single treatment regimen, the combination therapy yielded improved results regarding complete necrosis rate, tumor growth reduction, and overall survival (8,9,18). Combined therapy might have a synergistic effect for the following reasons: microwaves produce thermal energy through dielectric heating of water molecules in the affected tissue.…”

Section: Discussionmentioning

confidence: 99%

Study on the effect of chemoembolization combined with microwave ablation for the treatment of hepatocellular carcinoma in rats

Vogl

Qian²,

Tran³

et al. 2017

Diagn Interv Radiol

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H epatocellular carcinoma (HCC) is the fifth most common malignancy among men, and the seventh most common malignancy among women. Although morbidity and mortality are very high, no standardized treatment algorithm exists to date (1). Transarterial chemoembolization (TACE) is a frequently used interventional treatment for patients with inoperable HCC (2). Direct application of drugs into tumor feeding branches, allows for higher local chemotherapeutic concentrations with less systemic side effects. However, TACE has not been shown to notably prolong the overall survival rate, mainly due to local and distal tumor recurrence after treatment (3). Microwave ablation is a minimally invasive technique with low complication rate for the nonsurgical treatment of HCC (4). Electromagnetic waves at frequencies of 900-2450 MHz are used to induce coagulation necrosis. Polar molecules (mainly water dipoles) try to realign themselves with the direction of current in an electromagnetic field. The oscillation produced by constant realignment causes friction and a heating effect. However, it has been shown that local tumor control is highly dependent on complete tumor ablation, and recurrence in larger nodules (> 5 cm in diameter) is remarkably worse than in smaller ones (5, 6).Recently published studies imply that a combination of TACE and local ablation might have a synergistic effect on HCC (7). TACE leads to inflammatory edema, therefore increasing the watery content of the tumor, which the technique of microwave ablation uses to produce heat (8). Furthermore, central tumor parts in close vicinity to the probe receive the greatest thermal insult during physical ablation, while TACE works best on the better vascularized peripheral tumor areas (3). Trials with over 100 patients demonstrated that combined therapy of microwave ablation applied within six weeks after TACE can effective- 150From the Institute for Diagnostic and Interventional Radiology (T.J.V.  t.vogl@em.uni-frankfurt.de, A.T.,

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“…Moreover, edematous change (water retention) in the tumor and its surrounding area induced by ischemia and inflammation after TACE 15 was expected to enlarge the coagulation area, because microwaves act mainly on the watery component (water molecules) of tissues and produce dielectric heat. 16 Thus, increasing edematous change (water retention), could enlarge the area of tissue necrosis induced by microwave irradiation. Therefore, the PMCT procedure was performed 1-2 days after TACE to take advantage of the maximum degree of tissue ischemia and inflammation without any possibility of recanalization.…”

Section: Discussionmentioning

confidence: 99%