Baseline Visual Field Profile of Optic Neuritis

Keltner, John L.

doi:10.1001/archopht.1993.01090020085029

Cited by 176 publications

(32 citation statements)

References 18 publications

(3 reference statements)

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“…Therefore, the mean was calculated as follows: The original acuity values were converted to their logarithm, then the logarithms were averaged and finally the average was reconverted to an acuity value altitudinal, peripheral or diffuse. Specific criteria were not supplied, in order to make the procedure similar to previous studies in which the principal location of the visual field loss was not characterized in detail (ªcentral, altitudinal, Bjerrum, nasal step, depression of peripheral isopterº in [10]; ªcentral, superotemporal, superonasal, inferotemporal, inferonasalº in [16]). Only the visual field of the involved eye was available to the examiners; no other clinical findings were known.…”

Section: Classification Into Defect Types (Forced Choice)mentioning

confidence: 99%

“…Although a central scotoma has been regarded as the characteristic field defect of ON [2,4,5,9,11,12,13] and a sector scotoma as typical for AION [3,8,12,15], Rizzo and Lessell [16] found a considerable overlap of the visual field defects in ON and AION. Moreover, Keltner et al [10] concluded on the basis of 448 patients in the Optic Neuritis Treatment Trial: ªSince a wide variety of visual field defects can occur with an acute attack of optic neuritis, the pattern of visual field loss is of limited utility in distinguishing optic neuritis from ischemic optic neuropathy and other optic nerve disordersº. Aiming to solve this seeming contradiction, we investigated whether the visual fields are helpful in differentiating diagnosis between ON and AION.…”

Section: Introductionmentioning

confidence: 96%

See 1 more Smart Citation

Visual field defects in optic neuritis and anterior ischemic optic neuropathy: distinctive features

Gerling¹,

Meyer²,

Kommerell³

1998

Graefe's Archive for Clinical and Experimental Ophthalmology

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A sctoma centered on the fixation point with a sloping border is highly characteristic of ON, while an inferior altitudinal defect with a sharp border along the horizontal meridian, particularly in the nasal periphery, is highly characteristic of AION. To identify these diagnostic criteria, it can be necessary to examine full fields. With restriction of perimetry to 30 degrees a large central scotoma can be mistaken for a diffuse defect and the border in the nasal periphery can be missed.

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Section: Classification Into Defect Types (Forced Choice)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 96%

Visual field defects in optic neuritis and anterior ischemic optic neuropathy: distinctive features

Gerling¹,

Meyer²,

Kommerell³

1998

Graefe's Archive for Clinical and Experimental Ophthalmology

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“…This is a known but only rarely reported presentation of MS. Except for the ONTT [3], there have been few reports on a small number of patients in the literature concerning this type of presentation of MS [5, 6]. …”

Section: Discussionmentioning

confidence: 99%

“…In the Optic Neuritis Treatment Trial (ONTT), the frequency of baseline chiasmal and retrochiasmal visual field defects described clinically and at post-mortem examinations in 448 MS patients was 2.9% [3]. The same study also concluded that, although only 2.9% of MS patients had visual field evidence of a chiasmal or retrochiasmal lesion at baseline, in some patients this pattern may have been masked by the severity of visual acuity loss and that the chiasmal and retrochiasmal visual field defects increased considerably with follow-up visits [3]. We report a case presenting with homonymous hemianopsia as the initial manifestation of MS with total recovery of visual field defect in 2 weeks.…”

Section: Introductionmentioning

confidence: 99%

Homonymous Hemianopsia as the Initial Manifestation of Multiple Sclerosis

et al. 1998

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A 28-year-old male patient in good health with no previous neurologic or ophthalmoscopic abnormalities developed right homonymous hemianopsia. Magnetic resonance (MR) imaging demonstrated bilateral high-signal suprageniculate lesions. The lesion located in the left parieto-occipital area was compatible with the field defect observed. Oligoclonal bands were present in the cerebrospinal fluid. Testing of visual-evoked potentials revealed increased latencies in both eyes. The patient was given 1 g/day intravenous methylprednisolone for 3 days. The visual fields, as determined by automated static perimetry, recovered completely in 2 weeks. Follow-up MR imaging at 1 month showed no change compared to baseline. Seven months after the initial attack he suffered right internuclear ophthalmoplegia, which resolved spontaneously within 1 week. Based on the clinical and radiologic findings, the final diagnosis was made as clinically definite multiple sclerosis (MS). This patient represents a rare case of MS presenting first with homonymous hemianopsia.

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“…Varying patterns of field loss have been reported, ranging from altitudinal, arcuate and centrocaecal to diffuse and even unilateral hemianopic field defects. [1][2][3][4][5][6][7][8] Nearly all studies on visual fields in optic neuritis have been done using the standard automated perimetry, which has inadequate compensation for eye movements and this is particularly important in cases of poor vision and central scotomas such as those seen in optic neuritis. Microperimetry is a novel diagnostic modality that overcomes this limitation by continuously tracking the patient's fundus during stimulus projection.…”

Section: Introductionmentioning

confidence: 99%

Microperimetry in Optic Neuritis

Bhatia¹,

Lukhmana²,

Singh³

et al. 2016

Ophthalmol Open J

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Aim: To evaluate microperimetry as a tool for visual field assessment in optic neuritis and compare it with standard automated perimetry. Methods: A case-control study was conducted at a tertiary eye care centre in India. Ten cases of unilateral optic neuritis and 10 healthy controls underwent a detailed ophthalmic evaluation and visual field testing at presentation and 1 month and 3 months follow-up. Visual fields were charted using both the standard automated perimeter (10-2 and 30-2 programs) and microperimeter (central 20 degree program) at each visit. Results: The visual acuity at presentation of the affected eye, fellow eye and control eyes was 0.27±0.19, 0.93±0.14 and 0.94±0.17 respectively. The affected eye visual acuity improved significantly to 0.89±0.24 (p<0.001) at the 3 months follow-up visit. The mean sensitivity thresholds of 10-2 visual field test at presentation were 14.16±11.51, 30.40±1.98 and 31.04±1.95 respectively of which the affected eye showed a significant improvement over 3 months to 28.90±8.36 (p<0.001). The mean sensitivity thresholds of 30-2 visual field test at presentation were 12.88±10.32, 26.03±2.59 and 27.99±2.31 respectively of which the affected eye and fellow eye showed a significant improvement over 3 months to 26.02±7.54 (p<0.001) and 27.86±1.77 (p<0.03) respectively. The mean sensitivity thresholds of microperimetry 20 degree visual fields at presentation were 5.60±7.32, 16.54±1.46 and 17.30±1.64 respectively of which the affected eye showed a significant improvement over 3 months to 16.41±4.87 (p<0.001). Microperimetry fields did not improve completely at 1 month unlike the 10-2 fields and correlated strongly with visual recovery. The 30-2 fields were the most sensitive to determine subclinical affliction of the fellow eyes in optic neuritis. Conclusion: Microperimetry is a sensitive test to evaluate visual fields in optic neuritis and corresponds with visual recovery. The larger 30 degree module is still indispensible for visual field assessment in optic neuritis.

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Baseline Visual Field Profile of Optic Neuritis

Cited by 176 publications

References 18 publications

Visual field defects in optic neuritis and anterior ischemic optic neuropathy: distinctive features

Visual field defects in optic neuritis and anterior ischemic optic neuropathy: distinctive features

Homonymous Hemianopsia as the Initial Manifestation of Multiple Sclerosis

Microperimetry in Optic Neuritis

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