Baseline differences between vascular cognitive impairment no dementia reverters and non-reverters

Nyenhuis, David L.; Pedelty, Laura; Byrd, Sharon E.; Jhaveri, Miral D.; Wang, Changsheng; deToledo-Morrell, Leyla; Sripathirathan, Kumar; Gorelick, Philip B.

doi:10.1136/jnnp.2007.137554

Cited by 17 publications

(19 citation statements)

References 39 publications

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“…Seven studies investigated progression of patients with VCI-ND and reported changes in cognitive function or incident dementia rates [12,15,23,29,31,37,40], though the length of follow-up varied as well as whether cognitive test scores or dementia rates were examined over time, thus making comparison difficult (table 2). …”

Section: Resultsmentioning

confidence: 99%

“…Also used were the Clinical Dementia Rating (CDR) of 1+ [17], medical history [26,27], clinical diagnosis [29,30] and Mini Mental State Examination (MMSE) score ≤21 [33], or, in the case of one study, below the second percentile on the Korean MMSE [21]. Six studies excluded individuals using criteria for VaD [19,23,24,33,37,38]. …”

Section: Resultsmentioning

confidence: 99%

“…Cohorts were either population based (primary care) (n = 8) [11,12,13,14,15,16,17,18], hospital based (general secondary care) (n = 7) [19,20,21,22,23,24,25], specialist centres (tertiary care based, referred by a specialist clinic, e.g., memory, cardiovascular hospital clinic) (n = 14) [26,27,28,29,30,31,32,33,34,35,36,37,38] or mixed research centre and hospital based (n = 1) [39]. Many studies only included individuals above a certain age (e.g., ≥45 years [39], ≥65 years [11,12,13,14,15,16,18,34] or ≥75 years [17,20,25]).…”

Section: Resultsmentioning

confidence: 99%

“…Many studies only included individuals above a certain age (e.g., ≥45 years [39], ≥65 years [11,12,13,14,15,16,18,34] or ≥75 years [17,20,25]). Fourteen studies were based on populations with a previous history of stroke [19,20,21,22,23,24,25,26,27,28,37,38,39,40]. …”

Section: Resultsmentioning

confidence: 99%

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A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies

Harrison¹,

Tang²,

Keage³

et al. 2016

Dement Geriatr Cogn Disord

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Background/Aims: No set operational criteria for vascular cognitive impairment, no dementia (VCI-ND) have yet been established. The aim of this study is to undertake a systematic review to compare definitions of VCI-ND that have been used in cohort studies. Methods: Medline, PsycINFO and Embase were searched from inception to October 13, 2015. Initially, 3,142 records were screened, and 30 were included in this review. Results: No single set of criteria for defining VCI-ND was identified. VCI-NDwas broadly defined as an absence of dementia, cognitive impairment in at least one cognitive domain with signs of vascular involvement, and intact activities of daily living. Conclusion: Defining criteria will enable individuals with VCI-ND to be efficiently compared across cohort studies to more accurately determine the prevalence and risk of dementia.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies

Harrison¹,

Tang²,

Keage³

et al. 2016

Dement Geriatr Cogn Disord

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“…In a population study from Olmsted County, Minnesota, Kokmen et al [17] found that patients with a recent history of stroke had a ninefold [20]. In another study, frontal white matter hyperintensities on MRI were also associated with persistent cognitive changes after stroke [21].…”

Section: Vascular Risk Factors Transient Neurologic Attacks and Strmentioning

confidence: 97%

Vascular dementia: A review of recent evidence for prevention and treatment

Kirshner

2009

Curr Neurol Neurosci Rep

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Vascular dementia is a common cause of late-life cognitive decline. Vascular risk factors, transient ischemic attacks, silent and clinically evident strokes, and ischemic changes on brain imaging studies are all associated with the development of dementia. Prevention of vascular dementia involves treatment of risk factors and the same preventive measures used to avoid heart attacks and strokes. Other treatments for vascular dementia, although promising, remain unproved.

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White matter hyperintensities and longitudinal cognitive decline in cognitively normal populations and across diagnostic categories: A meta‐analysis, systematic review, and recommendations for future study harmonization

Roseborough

Saad

Goodman

et al. 2022

Alzheimer's & Dementia

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Introduction:The primary aim of this paper is to improve the clinical interpretation of white matter hyperintensities (WMHs) and provide an overarching summary of methodological approaches, allowing researchers to design future studies targeting current knowledge gaps. Methods:A meta-analysis and systematic review was performed investigating associations between baseline WMHs and longitudinal cognitive outcomes in cognitively normal populations, and populations with mild cognitive impairment (MCI), Alzheimer's disease (AD), and stroke.Results: Baseline WMHs increase the risk of cognitive impairment and dementia across diagnostic categories and most consistently in MCI and post-stroke populations.Apolipoprotein E (APOE) genotype and domain-specific cognitive changes relating to strategic anatomical locations, such as frontal WMH and executive decline, represent important considerations. Meta-analysis reliability was assessed using multiple methods of estimation, and results suggest that heterogeneity in study design and reporting remains a significant barrier. Discussion: Recommendations and future directions for study of WMHs are provided to improve cross-study comparison and translation of research into consistent clinical interpretation.

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Baseline differences between vascular cognitive impairment no dementia reverters and non-reverters

Abstract: These results suggest that Vascular CIND reversion may be a function of a combination of baseline neuropsychological function and location of cerebrovascular disease.

Cited by 17 publications

References 39 publications

A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies

A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies

Vascular dementia: A review of recent evidence for prevention and treatment

White matter hyperintensities and longitudinal cognitive decline in cognitively normal populations and across diagnostic categories: A meta‐analysis, systematic review, and recommendations for future study harmonization

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