Baseline Characteristics of Elderly Japanese Patients Aged ≥75 Years With Non-Valvular Atrial Fibrillation and a History of Stroke　― ANAFIE Registry ―

Abstract

age, 1,2 and aging is also an independent risk factor for stroke. 3,4 Thus, the optimal management of AF in elderly patients is important worldwide. Patients with AF aged ≥75 years, however, are often reported to be undertreated with oral anticoagulants E pidemiological data have clearly shown that atrial fibrillation (AF) is associated with an increased risk of ischemic stroke (IS), hemorrhagic consequences (including hemorrhagic stroke [HS] due to anticoagulation therapy), and death. 1 The prevalence of AF increases with

Impact of Previous Stroke on Clinical Outcome in Elderly Patients With Nonvalvular Atrial Fibrillation: ANAFIE Registry

“…4–7 To overcome these limitations, we designed a sub-analysis using data from the All Nippon AF in Elderly (ANAFIE) Registry, a nationwide, prospective registry study on elderly patients with NVAF. 10–13 The aim was to compare the long-term event incidence between elderly patients with NVAF and previous stroke/TIA and those without a history of stroke. Additionally, the effectiveness of direct OACs (DOACs) was evaluated in patients with NVAF and previous stroke/TIA.…”