Baseline cerebral oximetry values depend on non-modifiable patient characteristics

Valencia, Lucía; Rodríguez‐Pérez, Aurelio; Ojeda, Nazario; Santana, R.Y.; Morales, Laura; Padrón, Oto

doi:10.1016/j.accpm.2015.06.008

Cited by 9 publications

(5 citation statements)

References 17 publications

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“…In addition to age-dependence, other factors influencing rScO2 have been described. Valencia et al [25], for example, found a correlation between ASA status and baseline rScO2 in a small observational post-hoc analysis. Moreover, other correlations such as a dependence on body weight, height and renal function have also been described [25][26][27].…”

Section: Discussionmentioning

confidence: 97%

“…Valencia et al [25], for example, found a correlation between ASA status and baseline rScO2 in a small observational post-hoc analysis. Moreover, other correlations such as a dependence on body weight, height and renal function have also been described [25][26][27]. Therefore, it can be concluded that there are several factors that influence the rScO2 value, but a direct linear correlation has only been demonstrated for a limited number of factors.…”

Section: Discussionmentioning

confidence: 97%

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Preoperative cerebral oxygenation in high-risk noncardiac surgical patients: an observational study on postoperative mortality and complications

Baehner

Perlewitz

Ellerkmann

et al. 2023

J Clin Monit Comput

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Near Infrared Spectroscopy (NIRS) has become widely accepted to evaluate regional cerebral oxygen saturation (rScO2), potentially acting as a surrogate parameter of reduced cerebral oxygen delivery or increased consumption. Low preoperative rScO2 is associated with increased postoperative complications after cardiac surgery. However, its universal potential in pre-anesthesia risk assessment remains unclear. Therefore, we investigated whether low preoperative rScO2 is indicative of postoperative complications and associated with poor outcomes in noncardiac surgical patients. We prospectively enrolled 130 patients undergoing high-risk noncardiac surgery. During pre-anesthesia evaluation, baseline rScO2 was recorded with and without oxygen supplementation. The primary endpoint was 30-day mortality, while secondary endpoints were postoperative myocardial injury, respiratory complications, and renal failure. We further evaluated the impact of body position and preoperative hemoglobin (Hb) concentration on rScO2. Of the initially enrolled 130 patients, 126 remained for final analysis. Six (4.76%) patients died within 30 postoperative days. 95 (75.4%) patients were admitted to the ICU. 32 (25.4%) patients suffered from major postoperative complications. There was no significant association between rScO2 and 30-day mortality or secondary endpoints. Oxygen supplementation induced a significant increase of rScO2. Furthermore, Hb concentration correlated with rScO2 values and body position affected rScO2. No significant association between rScO2 values and NYHA, LVEF, or MET classes were observed. Preoperative rScO2 is not associated with postoperative complications in patients undergoing high-risk noncardiac surgery. We speculate that the discriminatory power of NIRS is insufficient due to individual variability of rScO2 values and confounding factors.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 97%

Preoperative cerebral oxygenation in high-risk noncardiac surgical patients: an observational study on postoperative mortality and complications

Baehner

Perlewitz

Ellerkmann

et al. 2023

J Clin Monit Comput

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“…In previous reports, only modest differences were noted between NIRS readings obtained with different techniques on the two sides of the forehead using two or more probes. 4,20,22,23 Most papers, however, report averages rather than individual per-patient data. In general, these differences were felt to be unimportant, and their pathophysiological meaning has not been investigated.…”

Section: Discussionmentioning

confidence: 99%

Ultrasound-tagged near-infrared spectroscopy does not disclose absent cerebral circulation in brain-dead adults

Caccioppola

Carbonara

Macri

et al. 2018

British Journal of Anaesthesia

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“…Cerebral oximetry non-invasively measures cerebral tissue oxygenation (SctO2) and has been shown to be informative in syncope evaluation on a head-up-tilt-test (HUT) [ 7 ]. Baseline SctO2 decreases with aging [ 8 ] but it is unknown whether the decrease in SctO2 is related to increased susceptibility to syncope during orthostatic provocation. By measuring SctO2 during HUT, age-related differences in SctO2 can be studied, together with their impact on developing reflex syncope and loss of consciousness.…”

Section: Introductionmentioning

confidence: 99%

The Influence of Age on Cerebral Tissue Oxygenation in Vasovagal Syncope and Orthostatic Hypotension

Kharraziha

Torabi

Johansson

et al. 2022

JCM

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Age-related physiological impairment increases susceptibility to syncope. We tested the hypotheses that cerebral oxygenation during orthostatic provocation, as well as the level at which syncope occurs, differs according to age. Non-invasive hemodynamic monitoring and cerebral oximetry were applied during a head-up tilt test in 139 patients with vasovagal syncope (mean (SD) 45, (17) years, 60%-female); 121 patients with orthostatic hypotension (61.4 (19.2) years, 49.6%-female); and 82 patients with a negative head-up tilt test (45 (18) years, 61%-female). Group differences in cerebral tissue oxygenation levels and systolic blood pressure were assessed in supine at 3 and 10 min of orthostatic provocation, 30 s before (i.e., presyncopal phase) and during syncope in age groups of <30, 30–60, and >60 years. During the head-up tilt test, cerebral tissue oxygenation at the presyncopal phase decreased with age, both in patients with vasovagal syncope (<30 years: 66.9 ± 6.2, 30–60: 64.5 ± 6.1, >60: 62.2 ± 5.8%; p = 0.009) and orthostatic hypotension (<30: 67.4 ± 4.4, 30–60: 61.6 ± 6.2, >60: 57.5 ± 3.9; p < 0.001). Mean systolic blood pressure at the presyncopal phase did not differ according to age. Cerebral oxygenation prior to syncope in older individuals with vasovagal syncope and orthostatic hypotension is lower compared with younger individuals independently of systolic blood pressure. This suggests that the level of cerebral oxygenation at which syncope is elected is lower in older individuals.

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Baseline cerebral oximetry values depend on non-modifiable patient characteristics

Cited by 9 publications

References 17 publications

Preoperative cerebral oxygenation in high-risk noncardiac surgical patients: an observational study on postoperative mortality and complications

Preoperative cerebral oxygenation in high-risk noncardiac surgical patients: an observational study on postoperative mortality and complications

Ultrasound-tagged near-infrared spectroscopy does not disclose absent cerebral circulation in brain-dead adults

The Influence of Age on Cerebral Tissue Oxygenation in Vasovagal Syncope and Orthostatic Hypotension

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