Base-promoted anaerobic intramolecular cyclization synthesis of 4,5-disubstituted-1,2,3-thiadiazoles

Abstract

A alkali-promoted, metal and oxidant-free method to construct 4,5-disubstituted-1,2,3-thiadiazoles from N-tosylhydrazone-bearing thiocarbamates by employing sustainable intramolecular reaction strategy has been developed. This reaction features high efficiency and good functional group...