Base-mediated reaction of vinyl bromides with aryl azides: one-pot synthesis of 1,5-disubstituted 1,2,3-triazoles

On Water Cu@g‐C3N4 Catalyzed Synthesis of NH‐1,2,3‐Triazoles via [2+3] Cycloadditions of Nitroolefins/Alkynes and Sodium Azide

“…Development of sustainable protocols for the synthesis of 1,2,3‐triazole scaffolds have emerged one of the thrust area of research for organic chemist due to their exclusive pharmaceutical, agrochemical, medicinal and many other applications . Several strategies have been reported for the synthesis of 1,2,3‐triazoles and Huisgen's dipolar cycloaddition of organic azides and alkynes is the most straightforward route . Subsequently, transition metal catalyzed alkyne‐azide cycloaddition (MAAC; M=Cu/Ag/Ru/Ir/Al) have been developed for the synthesis of 1,4 or 1,5‐disubstituted or 1,4,5‐trisubstituted triazoles .…”

Secondary Products from Intramolecular Cycloadditions of Azidoalkyl Enol Ethers and Azidoalkyl Vinyl Bromides: 1-Azadienes, Their Reactions with Diphenylketene, and Radical Cyclizations To Form Bi- and Tricyclic Lactams

“…Figure (w-Azidoalkyl)enol ethers (11)(12)(13), the products of their intramolecular cycloaddition (14,15), and triazoles formed by elimination (16)(17)(18).…”

CuO-Nanoparticles Catalyzed Synthesis of 1,4-Disubstituted-1,2,3-Triazoles from Bromoalkenes

“…3, Scheme 1). 43 Kuang et al, described Cu-catalyzed synthesis of 1H -1,2,3-triazoles from 1,1-dibromoalkenes and sodium azide. 44 Herein we report the synthesis of the complementary 1,4-disubstituted-1,2,3-triazoles from bromoalkenes and organic azides catalyzed by commercially available CuO nanoparticles (Eq.…”