Base hydrolysis kinetics and equilibria of [bis(2-pyridylmethyl)amine]chloroplatinum(II) and crystal and molecular structures of [Pt(bpma)Cl]Cl·H2O and [Pt(bpma)(OH2)](ClO4)2·2H2O

Cationic Pd(II)/Pt(II) 5,5-diethylbarbiturate complexes with bis(2-pyridylmethyl)amine and terpyridine: Synthesis, structures,DNA/BSA interactions, intracellular distribution, cytotoxic activity and induction of apoptosis

“…2). The M-N(bpma) bond distances are normal and comparable to those of other closely related complexes [22,23,[33][34][35]. On the other hand, 3 and 4 are isostructural, consisting of a [M(barb)(terpy)] + cation, a nitrate counterion and lattice water molecules (Fig.…”

“…The precursor complexes, namely [MCl(bpma)]Cl·H 2 O [22,23] and [MCl(terpy)]Cl·2H 2 O [24,25] (M = Pd II or Pt II ), were prepared following the literature methods. Tris(hydroxymethyl)aminomethane hydrochloride (TrisHCl), ethidium bromide (EB), Hoechst 33258, pBR322 plasmid DNA, FS-DNA and BSA were obtained from Sigma, and loading buffer (10×) from was obtained from Dr. Zeydanli.…”

The Relative Coordinating Ability of Some Weak O‐Donor Anions and Water Towards the [Pt(terpy)]2+ (terpy = 2,2′:6′,2″‐terpyridine) Center – X‐ray Crystal Structures of [Pt(terpy)(H2O)](CF3SO3)2 and [Pt2(μ‐OH)(terpy)2](PF6)2(CF3SO3)

“…The Pt-OH 2 distance [2.040(5) Å] compares well with the distances observed in Pt II square-planar complexes where a water molecule is trans to a nitrogen atom (range: 2.05-2.10 Å). [24] No stacking interactions between parallel molecular planes shorter than the sum of the van der Waals radii are observed.…”

“…The Pt-O distances between the platinum atoms and the negatively charged bridging hydroxido group [2.033(6) and 2.024(6) Å] are slightly shorter than the Pt-O(water) distances (2.04-2.10 Å) observed in the previous structure (8Ј) and in square-planar Pt II complexes where a water molecule is trans to a nitrogen atom. [24] The hydroxido group is hydrogen-bonded to the disordered triflate anion with an O1···O2 distance of 2.656(15) Å (Figure 3).…”

Mechanistic studies on the reactions of platinum(ii) complexes with nitrogen- and sulfur-donor biomolecules

“…The substitution reactions of [Pt(bpma)Cl] + were studied with thiols, 71 pyridine and derivatives of pyridine. 72 It is interesting that the aqua complex [Pt(bpma)(H 2 O)] 2+ , which crystallises with perchlorate as counter ions, acts as a diprotic acid for which the second deprotonation step involves the coordinated amine group. 72 In addition, ligands with mixed donor atoms, viz.…”