Basaloid squamous cell carcinoma of the palate

Abstract

considered to be a malignant lymphoma until immunostaining methods were applied. The nodular transformation of splenic red pulp in our three cases has not been seen without accompanying carcinomatous involvement. Therefore, it seems likely that this distinctive nodular pattern is caused by the infiltration of the metastatic tumour cells in the red pulp and accompanied by a desmoplastic stromal response. The degree of desmoplasia in the primary sites in our cases was generally low but the fibrosis of splenic red pulp was marked. The exact role of the tumour cells and of other factors in producing the nodular transformation of splenic red pulp is not established.We recently published a paper in which we reported a papillary carcinoma of the thyroid, which caused exuberant desmoplastic response within the thyroid and surrounding soft tissue resembling nodular fasciitis. The metastatic foci of the same carcinoma within the parathyroid gland and cervical lymph node grew without associated fasciitis-like stroma'. This case and the present cases suggest the importance of the microenvironment in the degree of desmoplasia that metastatic tumours can cause. References1. Harman JW. Dacorso P. Spread of carcinoma to the spleen. Arch. 2. Hirst AE. Bullock WK. Metastatic carcinoma of the spleen. Am. I. 3. Marymont JH. Gross S. Patterns of metastatic cancer in the spleen. 4. Berge T. Splenic metastases. Frequencies and patterns. APMIS [A] 5. Klein €3. Stein M. Kuten A et al. Splenomegaly and solilary spleen metastasis in solid tumors. Cancer 1987: 60; 100-102. 6. Michal M. Chlumska A, Fakan F. Papillary carcinoma of thyroid with exuberant nodular fasciitis-like stroma.

Basaloid Squamous Cell Carcinoma of the Head and Neck

“… 1,17–25 Other head and neck sites include the palate, buccal cavity, floor of mouth, nasopharynx, trachea, and sinonasal tract. 2–9 BSCC is not limited to the head and neck region but has also been described in the esophagus, lung, thymus, anus, and cervix, among other sites. 10–16 …”

“… 1 Since its initial description, BSCC has also been described in other head and neck sites such as the palate, buccal cavity, floor of mouth, nasopharynx, trachea, and sinonasal tract. 2–9 Although BSCC has predilection for the head and neck region, this tumor can also occur at other sites such as the esophagus, lung, thymus, anus, and cervix. 10–16 BSCC is considered an aggressive form of squamous cell carcinoma, with cases often presenting in advanced stages and often with metastases.…”

Basaloid Squamous Cell Carcinoma of the Head and Neck

“…Upper aerodigestive tract is the most common site of origin of this tumour in the head and neck [2,3], especially epiglottis, hypopharynx (piriform sinus) and base of the tongue [4,5]. Other less common sites of origin in this region include floor of the mouth, oral mucosa, palate, tonsils, sinonasal tract, nasopharynx, and trachea [6][7][8][9][10][11]. Additionally, BSCC has been reported in oesophagus, lung, anus, cervix uteri, penis and urinary bladder [12][13][14][15][16][17].…”

Polypoid carcinoma of the tongue

“…Because of its varied morphologic appearance, illustrations of the alleged BSC are different from case to case (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). Certain cases can resemble SCC.…”