Basal Cell Epithelioma with Dermal Melanocytes

Abstract

We observed dermal melanocytes running in parallel with collagen fibers in the peritumoral stroma of a basal cell epithelioma. The dermal melanocyte contained many free mature melanosomes. They frequently showed an intimate contact with elastic fibers and were surrounded by an extracellular sheath with elastic fibers. These cells may have occurred due to the activation of dormant dermal melanocytes following the appearance of basal cell epithelioma, which may have been derived from a nevoid tumor originating from dormant, latent embryonic foci.

Acquired Dermal Melanocytosis of the Hand: A New Clinical Type of Dermal Melanocytosis

“…It is said that, at birth, melanoeytes may be present in the dermal portion of the skin ofthe scalp, the backs of the hands, and the sacrum, but they disappear shortly after birth (12). Mongolian spot (1), nevus of Ota (2), nevus ofIto (3), acquired symmetrical dermal melanocytosis of the face (4-6) and some other conditions (13)(14)(15) are grouped as dermal melanoeytosis. Mongolian spot (1,16) and dermal melanocyte hamartoma (13) are congenital.…”

Late Onset Dermal Melanocytosis: An Upper Back Variant

“…The newest addition to this list is the acquired bilateral nevus composed of Ota-like macules (1). Dermal melanocytes have occasionally been detected in seemingly unrelated conditions, such as basal cell carcinoma (2) and cleft lip (3).…”

Angiosarcoma with dermal melanocytosis

“…There have been reports of dermal melanocytosis or dermal nevi of melanocytic origin, occurring in combination with skin tumors of epidermal or adnexal origin (1)(2)(3)(4). However, dermal melanocytosis with a tumor of vascular origin has apparently not been reported to date.…”