Basal cell carcinoma of the vulva

Piura, Benjamin; Rabinovich, Alex; Dgani, R.

doi:10.1002/(sici)1096-9098(199903)70:3<172::aid-jso5>3.0.co;2-i

Cited by 42 publications

(34 citation statements)

References 15 publications

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“…Metastases may occur particularly in case of the sclerosing type and those with perineural invasion. In our case, any perineural invasion and lymphovascular involvement were not observed (7,14). It was thought for many years that metastases did not occur; therefore, it was considered that the lesion could be treated by wide local excision.…”

Section: Discussionmentioning

confidence: 50%

“…Bleeding, palpable vulvar massor swelling, ulceration, irritation, pain, and pruritis are most common seen symptoms (6,7). The tumor is typically solitary and its size is ranged between 0.2 and 10 cm and most often located on the labium majus and less commonly on the labium minus, urethral meatus, and clitoris (7,8). In a review of 63 cases of vulvar BCC, the reported mean age of patients was 70 year-old, the mean lesion size was 2.1 cm and 28% of the lesions presented as ulcerative and 3% as pigmented.…”

Section: Discussionmentioning

confidence: 99%

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Basal cell carcinoma of the vulva: A case report

2015

Eur J Med Sci

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Basal cell carcinoma (BCC) is usually observed on sun exposed skin areas such as head and neck. However, BCC may also seen areas which are not exposed to sunlight such as perianal and genital regions. Vulvar BCC is seen rare and account for less than 5% of vulvar cancers and less than 1% of all BCCs. In this paper, we report a rare case of locally invasive BCC located at the left labium majus of a 55-year-old woman treated with local wide surgical excision. The physical examination revealed a 0.8x0.8 cm and exophytic lesion. The histopathologic diagnosis was nodular type BCC. All surgical margins of specimen was free of tumor. The neoplastic cells showed diffuse positive nuclear immunoreactivity for p53 and Ki-67, immunohistologically. The patient recovered without any complication.

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Section: Discussionmentioning

confidence: 50%

Section: Discussionmentioning

confidence: 99%

Basal cell carcinoma of the vulva: A case report

2015

Eur J Med Sci

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“…They are not common on the vulva and accounted for only 7% of all vulvar cancers in one study. 31 They usually occur on the outer labia majora and are often nodular but may ulcerate. Verrucous carcinomas are uncommon.…”

Section: Premalignancymentioning

confidence: 99%

An Overview of Vulvar Ulceration

Lewis¹,

Velangi²

2005

Clinical Obstetrics and Gynecology

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“…BCC accounts for 2–4% of all vulvar cancers (Table 1) and occurs most commonly in post-menopausal women 4. Since its first description by Temesvary in 1926, 200 cases of vulvar BCC have been listed in the literature 5. The etiology of vulvar BCC is unknown.…”

Section: Introductionmentioning

confidence: 99%

“…The etiology of vulvar BCC is unknown. Syphilis, chronic irritation, chronic infection, trauma, arsenicals, and radiotherapy have been implicated as possible precipitating factors 56. Clinically, vulvar BCC is an indolent and destructive tumor that rarely metastases, but the local recurrence rate is as high as 20% in some series 56…”

Section: Introductionmentioning

confidence: 99%

An unusual location of basal cell carcinoma: The clitoris and the vulva

et al. 2008

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Vulvar basal cell carcinoma (BCC) is rare, accounting for less than 5% of all vulvar neoplasms and less than 1% of all BCCs. Vulvar BCCs are usually diagnosed late because they are often asymptomatic and tend to grow at slow rates. They may be invasive and destructive if neglected or improperly treated. Nevertheless, they have a very low propensity for metastatic spread, but frequently recur after simple excision. We report a 78 year-old woman presenting with the complaint of painful vulvar ulceration and vaginal bleeding. The physical examination revealed a 3 × 2 cm indurated nodulo-ulcerative lesion involving the clitoris, both labia minora and left labium majus. The histopathology was consistent with the “solid type BCC” that invaded the subcutaneous tissue without lymph node metastasis. The patient underwent wide local excision with clitoral amputation and remained disease free at post-surgical follow-up after 18 months.

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Basal cell carcinoma of the vulva

Cited by 42 publications

References 15 publications

Basal cell carcinoma of the vulva: A case report

Basal cell carcinoma of the vulva: A case report

An Overview of Vulvar Ulceration

An unusual location of basal cell carcinoma: The clitoris and the vulva

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