Basal Cell Carcinoma of the Male Breast

Basal Cell Carcinoma of the Male Nipple Case Report and Review of the Literature

“…Basal cell carcinoma is a tumor arising mostly on sun‐damaged skin. Twelve of the 16 cases of BCC of the nipple so far described arose in men 1–13 (see Table 1). This predominance has been theoretically related to an increased exposure of the chest area to sunlight in men 11–13 .…”

Secondary Intention Healing following Mohs Micrographic Surgery for Basal Cell Carcinoma of the Nipple and Areola*

“…Those with a higher risk of metastasizing are large, neglected tumours, those invading bone with a morpheafonn and infiltrative tumour histology ( 14). Three of the 31 BCCs of the nipple-areola complex reported have apparent axillary lymph node involvement (15)(16)(17). Only one histologically confirmed the presence of BCC in the axillary lymph nodes (15); a case that reports a 54-year-old man who had had a nipple resection followed by radiotherapy for BCC of the left nipple 4 years prior to presenting with discomfort under his left arm on movement and radiation changes on the left breast.…”

“…Etretinate has also been used for 3 months in one case, with complete resolution of the BCC confirmed histologically (18). Four of the 31 cases were treated with mastectomy (16,19,20) and one with a partial mastectomy (11). So far only five cases have been treated with MMS, two with infiltrating histology (4,5,10,21,22).…”

Pigmented Basal Cell Carcinoma of the Nipple-Areola Complex in an Elderly Woman

“…The lesion was treated with a wide local excision so as to spare tissue. Because some authors maintain that BCC of the NAC has a higher metastatic potential than BCC at other sites16-18, minimally disfiguring surgery with concurrent sentinel node biopsy, such as Mohs' micrographic surgery or postoperative radiotherapy, might be recommended3,16,19. A higher-grade malignancy of BCC of the NAC can be explained by the rich angiolymphatic supply to the nipple, which may provide a direct route for the tumor to spread5.…”