Basal cell carcinoma in five albino Africans from the south‐eastern equatorial rain forest of Nigeria

Asuquo, Maurice E.; Agweye, Pius; Ugare, Gabriel; Ebughe, Godwin

doi:10.1111/j.1365-4632.2007.03272.x

Cited by 24 publications

(19 citation statements)

References 15 publications

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“…In this study, the majority of patients were albinos accounting for 58.3% of cases and the head was the most frequent anatomical site affected. Similar anatomical site distribution was also reported in other studies (Feldman et al, 2001;Samaila & Adewuyi, 2005;Asuquo et al, 2007). The occurrence of these tumours in sun-exposed parts of the body suggests the role of solar radiation as a risk factor in skin cancer in albinos.…”

Section: Discussionsupporting

confidence: 87%

Dermatological malignancies at a University teaching Hospital in Northwestern Tanzania: A retrospective review of 154 cases

Chalya

Gilyoma

Kanumba³

et al. 2012

Tanzania J Hlth Res

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Dermatological malignancies are among the most common form of cancers and the global incidence has been increasing at an alarming rate. A retrospective study was conducted to determine the prevalence, histopathological pattern, anatomical distribution and treatment outcome of dermatological malignancies at Bugando Medical Centre in North-western Tanzania. Data were collected from patients' files kept in the Medical record department; the surgical wards, operating theatre and histopathology laboratory and analyzed using Statistical package for social sciences system. A total of 154 patients with a histopathological diagnosis of dermatological malignancy were studied. Generally, males outnumbered females by a ratio of 1.4:1. The majority of patients were in the 5th and 6th decades of life. Malignant melanoma was the most common dermatological malignancy (67.5%) followed by Kaposi's sarcoma (10.4%), Squamous cell carcinoma (8.4%) and Basal cell carcinoma(7.8%). The lower limbs were the most frequent site accounting for 55.8%. Wide local excision was the most common surgical procedure performed in 79.2% of cases. Post-operative wound infection was the most common complication in 58.3% of patients. Mortality rate was 3.8%. Dermatological malignancies are more prevalent in our setting. A high index of suspicion is needed to avoid labelling malignancies "chronic ulcers" and all suspected lesions should be biopsed. ______________________________________________________________________________

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Section: Discussionsupporting

confidence: 87%

Dermatological malignancies at a University teaching Hospital in Northwestern Tanzania: A retrospective review of 154 cases

Chalya

Gilyoma

Kanumba³

et al. 2012

Tanzania J Hlth Res

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“…1). In an earlier report from this center, we found BCC only in albinos, highlighting the effectiveness of protection against solar radiation provided by melanin; 10 however, Ademuluyi and Ijaduola 11 reported the occurrence of BCC of the head and neck in 16 (26.72%) albinos and 44 (73.28%) Negroid patients in northern Nigeria. This variation may be a result of environmental differences between the northern and southern regions and, possibly, ethnicity.…”

Section: Discussionmentioning

confidence: 50%

Skin cancers amongst four Nigerian albinos

Asuquo

Ngim

Ebughe

et al. 2009

International Journal of Dermatology

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“…In our previous report, we found BCC only in albinos [27]. Our recent experience revealed that the two patients were blacks and the lesions were found on the head, Fig.…”

Section: Discussionmentioning

confidence: 86%

Skin malignancies in Calabar, Southern Nigeria

et al. 2009

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Background: Skin cancers are among the most common form of cancer. In Africa, several reports reveal squamous cell carcinoma (SCC) as the commonest skin malignancy. In Africa, including regions of the same country, there are significant differences in the pattern of skin malignancy. This study sought to evaluate the pattern, risk factors and outcome of management of skin malignancy in our setting. Methods: Patients with histologic diagnoses of skin malignancy from January 2007 and December 2008 who presented to the University of Calabar Teaching Hospital were prospectively studied. Results: Forty-five patients presented with skin malignancy during the study period. The ages of the patients ranged from 5 and 75 years (mean: 46.6 years). The commonest skin malignancy was SCC in 19 (42.2%) patients while Kaposi sarcoma (KS) ranked second 15 (33.3%). Six patients presented with melanoma, two with metastatic carcinoma, basal cell carcinoma (BCC) two patients and a patient with dermatofibrosarcoma protuberans (DFSP). The lower limb was the commonest site involved in 25 (55.6%) patients, while the head and neck 11 (24.4%) ranked second. Conclusion: SCC was the commonest skin malignancy. Non-solar factors of chronic ulcers in SCC, immunosuppression in KS, were identified as possible risk factors in some malignancies. This is at variance with the experience in Caucasians where solar radiation is the predominant risk factor. However, albinism and solar radiation were identified as risk factors in keeping with the Caucasians. Health education strategies on prevention, early presentation, and surgical evaluation of chronic ulcers would improve outcome.

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Basal cell carcinoma in five albino Africans from the south‐eastern equatorial rain forest of Nigeria

Abstract: Albinism and environmental exposure to ultraviolet light were identified as risk factors for the development of BCC. Implementation of public education strategies concerning prevention would improve the prognosis and healthcare costs associated with these tumors.

Cited by 24 publications

References 15 publications

Dermatological malignancies at a University teaching Hospital in Northwestern Tanzania: A retrospective review of 154 cases

Dermatological malignancies at a University teaching Hospital in Northwestern Tanzania: A retrospective review of 154 cases

Skin cancers amongst four Nigerian albinos

Skin malignancies in Calabar, Southern Nigeria

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