Basal-cell carcinoma complicating a port-wine stain

Abstract

A rare radio-resistant basal-cell carcinoma is described which presented as a recently enlarged non-ulcerated nodule on a port-wine stain. The literature on basal-cell carcinoma occurring on a port-wine stain is reviewed, and the aetiological significance of thorium-X, sun-exposure and vascular changes in the development of malignancy on this type of haemangioma is discussed.

Willingness to pay and time trade-off: useful utility indicators for the assessment of quality of life and patient satisfaction in patients with port wine stains

“…Port wine stains are congenital vascular malformations with an incidence of 2% of births 1 . As malignant transformation occurs only very rarely, 2,3 patients mainly suffer from cosmetic problems especially when lesions are located on the face. Two recent studies analysed impairment of quality of life in patients with port wine stains 4,5 .…”

Basal cell carcinoma arising over facial port wine stain: a single‐centre experience

“…This is also true for BCCs in PWSs, with the exception of two early cases in adolescents (10 and 16 years old) reported by Rogers 9 and Courtemanche 11 . The role of sunlight and skin type is supported by the rare cases of BCC development in untreated PWSs 10,12,14–16 . Furthermore, most of the reported cases appeared in sun‐exposed areas, mainly the face.…”

“…The majority of BCCs developing in PWS (around 75%) follow previous radiotherapy. There are only few cases of genuine BCCs in PWS with no previous radiotherapy 10,12,14,15,20 . PWS seems to be relatively immune to BCCs.…”

“…BCC arising in a PWS or nevus flammeus is a rare finding, although reports date back to the last quarter of the radiotherapy era 9–23 . The present prospective evaluation for the presence of signs of BCC in patients being treated in our centre for PWS was prompted by the increasing number of publications suggesting a connection between these entities.…”

Spindle Cell Carcinoma Arising in a Port-Wine Stain

“…In the English literature, to our knowledge, several cases of basal cell carcinoma [4][5][6][7][8][9][10] and only 1 case of squamous cell carcinoma [ 111 aris ing in a PWS have been reported. However, half the patients with basal cell carcinoma and the patient with squamous cell carcinoma had received radiation treatments previously, which are considered to be related to the pathoToshivuki Kitajima…”