“…Several different tumors of epidermal, adnexal, and mesenchymal origin are known to arise (one or more simultaneously [24,25,26]). Benign tumors [12,27,28,29,30,31,32] are the most common neoplasms, including syringocystadenoma papilliferum, apocrine cystadenoma, trichoblastoma, trichilemmal cysts, and keratoacanthoma. Although less common, malignant degeneration [33,34,35,36,37,38,39,40,41,42,43,44,45,46,47] occurs, with a lifetime risk of 5-20%.…”