Basal cell carcinoma: an updated epidemiological and therapeutically profile of an urban population

Abstract

The factors related to the development of basal cell cancer which were significantly present in the population surveyed were: older age, white individuals, phototypes I and II, presence of actinic keratosis, previous history of non-melanoma skin cancer and exposure to ultra-violet rays both in recreational and in occupational form. The surgical treatment employed was effective with a rate of incomplete excision and recurrence similar to those found in the literature.

Epidemiologia dos carcinomas basocelulares em Tubarão, Santa Catarina (SC), Brasil, entre 1999 e 2008

“…6,9,18 There was no difference in the incidence of BCC in relation to gender; 51.2% of the cases involved females, which corroborates with data from the scientific literature. 6,8,19 Cases predominated in individuals between 61 and 80 years old (43.4%), similar to works developed by Bariani and Silveira, which showed 59% and 50% of the BCC cases in this age range. 8,19 This could be explained by the fact that older individuals have a less efficient immune system, with lower capacity of DNA regeneration, 9,16,20 and are more exposed to BCC risk factors, especially due to the cumulative effect of intense and continuous sun exposure.…”

“…6,8,19 Cases predominated in individuals between 61 and 80 years old (43.4%), similar to works developed by Bariani and Silveira, which showed 59% and 50% of the BCC cases in this age range. 8,19 This could be explained by the fact that older individuals have a less efficient immune system, with lower capacity of DNA regeneration, 9,16,20 and are more exposed to BCC risk factors, especially due to the cumulative effect of intense and continuous sun exposure. 9,15 Most skin cancers occur in areas of the body frequently exposed to the sun.…”

“…6,8,9,15,21,22 In this study, 67.7% of the BCCs were localized in the cephalic region, similar to the percentage found in the literature, which varied from 52.1 to 86%. 6,19,21,23,24 This finding strengthens the relevance of chronic sun exposure as a risk factor, with the face being highly exposed to the sun. Incidence in the trunk was 19.6% and was more frequent in men (p<0.001).…”

“…This incidence was similar to the one found in the study conducted in Blumenau (SC), but different from those of studies conducted in other Brazilian regions. 6,19 Perhaps this difference occurred due to the characteristics of Tubarão and Blumenau, since agriculture is a very important economic activity in these regions and is mostly practiced by men who expose themselves to the sun without protection. In addition, it is common for men to be outdoors on very hot days without a physical (shirt) and chemical (sunscreen) barrier due to cultural characteristics.…”

A study of basal cell carcinoma in South Asians for risk factor and clinicopathological characterization: A hospital based study

“…The cases belonged to age ranging from 29 to 92 years which is similar to study published from North India [23]. Higher rates of occurrence of BCC among elderly may be due to cumulative UVR induced DNA damage [24] as well as reduced efficiency of immune-surveillance and DNA repair mechanisms with aging [25]. In our study, higher frequency among rural inhabitants was seen when compared to urban residents.…”