Basal Cell Carcinoma After Treatment of Childhood Acute Lymphoblastic Leukemia and Concise Review of the Literature

Ünal, Şule; Çetin, Mualla; Gümrük, Fatma

doi:10.1111/pde.12559

Cited by 5 publications

(1 citation statement)

References 21 publications

(28 reference statements)

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“…1 Prolonged immunosuppression, radiation therapy, and voriconazole therapy are established in the adult literature as iatrogenic risk factors for NMSC but have only been reported anecdotally in children. [2][3][4] Given the increasing number of long-term survivors from childhood cancer and other chronic medical conditions, pediatric cases of NMSC caused by iatrogenic risk factors may be more common than previously reported. We sought to explore the characteristics of and potential risk factors for NMSC in children and young adults.…”

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confidence: 99%

Characteristics and outcomes of nonmelanoma skin cancer (NMSC) in children and young adults

Khosravi

Schmidt

Huang

2015

Journal of the American Academy of Dermatology

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My role in this manuscript included: preparation of the IRB protocol for submission, review of 28 patient charts with subsequent documentation in Excel, identification of risk factors for retrospective review, data analysis, initial preparation of the draft detailing the outcomes of our findings, and responding to journal editors. When reviewing the charts, we looked for patients with squamous cell and basal cell carcinomas diagnosed between 1993 and 2014; I recorded demographic data (including Fitzpatrick type, age, ethnicity, and gender), medical history (malignancy, stem-cell or organ transplantation, genetic syndromes), medication history (chemotherapeutic and immunosuppressive agents), radiation exposure (total body irradiation and localized radiation therapy), histopathology records, delays in diagnoses, and modality of treatment. Data analysis that was performed included descriptive analysis, fisher exact test, and unpaired t test. Upon review of the paper by the journal, I also prepared our initial response to each of their concerns and finalized the paper for publication. My mentor in this project, Dr. Jennifer T. Huang, provided the initial idea for the project and patient database for review. She approved and modified the risk factors and variables that we would evaluate in our review of each patient. In addition, she guided me on the analysis of our findings and edited the paper to effectively relay our results and thoughts to the medical community. Lastly, our collaborator, Dr. Birgitta Schmidt, reviewed the pathology of each patient's cutaneous malignancy to ensure proper diagnosis.

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confidence: 99%