Basal Cell Adenoma: Distinctive Tumor of Salivary Glands

Bernacki, Edward G.; Batsakis, John G.; Johns, Michael E.

doi:10.1001/archotol.1974.00780030090002

Cited by 64 publications

(17 citation statements)

References 3 publications

(3 reference statements)

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“…These encapsulated tumours do not exceed 3 cm in diameter and are superficially located in the glandular body with a brownish appearance. An unusual feature of this case was that the age of patient was 23 years, in contrast to reported age of occurrence-57.7 years-and correlated to its female predilection [4,5].…”

Section: Discussioncontrasting

confidence: 57%

Basal Cell Adenoma of Submandibular Salivary Gland: A Case Report and Literature Review

Lambade¹,

Rajkhokar²,

Lambade

2014

J. Maxillofac. Oral Surg.

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Background Salivary gland tumours constitute about 3-4 % of all head and neck neoplasms. Approximately 80 % originate in the parotid gland and they are rarely present in the submandibular gland. Basal cell adenoma is a benign epithelial salivary gland tumour that appears to have unique histologic characteristics. The diagnosis of this entity must be established by histological study. Case report The literature revealed only four reported cases of basal cell adenoma of submandibular salivary gland. This article presents a rarely occurring basal cell adenoma as a fifth reported case in submandibular salivary gland in a 23 year old female. Discussion A rare case of basal cell adenoma of submandibular salivary gland is reported with clinical features, diagnosis, histopathological features and treatment modalities. When there is involvement of submandibular gland with a tumour the histopathological confirmation is mandatory instead of relying on FNAC and it must be differentiated from pleomorphic adenoma, adenoid cystic carcinoma, adenocarcinoma due to its prognostic implications.Conclusion Entities like basal cell adenoma can only be established by histopathological examination after excisional biopsy. The treatment done also affects the ultimate prognosis. As such the surgeon has to make his clinical decision based on many factors like history, clinical examination, histopathological examinations, radiological examination and immunohistochemistry study. No single criteria should be relied upon. We recommend to carry out genetic pattern study in a person with basal cell adenoma to rule out pathogenesis and establish a correct diagnosis of it for better understanding and prognosis.

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Section: Discussioncontrasting

confidence: 57%

Basal Cell Adenoma of Submandibular Salivary Gland: A Case Report and Literature Review

Lambade¹,

Rajkhokar²,

Lambade

2014

J. Maxillofac. Oral Surg.

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“…As cited by Bernacki et al (11), 11 cases of basal cell adenoma of minor salivary glands were reported by Cbrist and Crocker (12). Some (13) credit Kleinsasser and Klein (14) with having introduced tbe designation basal cell adenoma of salivary gland in tbe German literature in 1967.…”

Section: Discussionmentioning

confidence: 96%

Multiple malignant cylindromas of skin in association with basel cell adenocarcinoma with adenoid cystic features of minor salivary gland

Antonescu

Terzakis

1997

J Cutan Pathol

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This unusual case is that of a middle-aged man exhibiting a tumor diathesis including a basal cell adenocarcinoma with features of adenoid cystic carcinoma arising in minor salivary gland of lip in association with multiple primary malignant cylindromas of skin. The labial lesion showed invasive tubules, solid epithelial sheets and cribriform structures. It did not exhibit PAS positive juxta-tubular basement membrane material. The skin lesions all showed features of a highly infiltrative cylindromatous carcinoma with two cell types, peripheral palisading and prominent PAS positive juxta-tubular basement membrane material. Immunocytochemical studies of the lip lesion and one of the skin lesions showed similarities, including positive staining for high and low molecular weight keratins and S-100 with negative staining for CEA. The precious descriptions of tumor diatheses involving dermal cylindromas and dermal analogue tumors of salivary glands and the distinctions with the present study are noted. If benign and even malignant cylindromas were described in the literature to be associated with basal cell adenocarcinoma of the major salivary glands, our case is unique by its association with this rare malignant tumor in a minor salivary gland.

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“…It is a firm mobile painless mass. It is usually superficial within the glandular body, and a brownish appearance is usually observed [9]. The most frequent location is the parotid gland, although other sites are possible, such as the upper lip, buccal mucosa, lower lip, palate and nasal septum.…”

Section: Discussionmentioning

confidence: 99%

Basal Cell Adenoma of Parotid Gland: Case Report and Review of Literature

Kanaujia

Singh

Nautiyal

et al. 2015

Indian J Otolaryngol Head Neck Surg

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Basal cell adenoma (BCA) of the salivary gland is a rare neoplasm consists of a monomorphic population of basaloid epithelial cells, and it accounts for approximately 1-2 % of all salivary gland tumors. Its most frequent location is the parotid gland. It usually appears as a firm and mobile slow-growing mass. Histologically, isomorphic cells in nests and interlaced trabecules with a prominent basal membrane are observed. In contrast to pleomorphic adenoma, it tends to be multiple and its recurrence rate after surgical excision is high. Due to prognostic implications, differential diagnosis with basal cell adenocarcinoma, adenoid cystic carcinoma and basaloid squamous cell carcinoma is mandatory. We report a case of BCA of the parotid gland. We also review the literature and discuss the diagnosis and management of this rare entity.

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Basal Cell Adenoma: Distinctive Tumor of Salivary Glands

Cited by 64 publications

References 3 publications

Basal Cell Adenoma of Submandibular Salivary Gland: A Case Report and Literature Review

Basal Cell Adenoma of Submandibular Salivary Gland: A Case Report and Literature Review

Multiple malignant cylindromas of skin in association with basel cell adenocarcinoma with adenoid cystic features of minor salivary gland

Basal Cell Adenoma of Parotid Gland: Case Report and Review of Literature

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