Bartonellosis, One Health and all creatures great and small

Breitschwerdt, Edward B.

doi:10.1002/9781119278368.ch5.2

Cited by 31 publications

(50 citation statements)

References 81 publications

(60 reference statements)

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“…Recently, an increasing number of Bartonella species have been emerged to cause human diseases (Breitschwerdt, ). This scenario encourages the search for animal reservoirs of novel species of Bartonella in an attempt to understand the ecology of the illnesses collectively known as bartonelloses.…”

Section: Introductionmentioning

confidence: 99%

Genetic diversity ofBartonellaspp. in vampire bats from Brazil

André

Gutiérrez

Ikeda

et al. 2019

Transbound Emerg Dis

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Recently, an increasing number of Bartonella species have been emerged to cause human diseases. Among animal reservoirs for Bartonella spp., bats stand out due to their high mobility, wide distribution, social behaviour and long‐life span. Although studies on the role of vampire bats in the epidemiology of rabies have been extensively investigated in Latin America, information on the circulation and genetic diversity of Bartonella species in these bat species is scarce. In the present work, 208 vampire bats, namely Desmodus rotundus (the common vampire bat; n = 167), Diphylla ecaudata (the hairy‐legged vampire bat; n = 32) and Diaemus youngii (the white‐winged vampire bat; n = 9) from 15 different states in Brazil were sampled. DNA was extracted from liver tissue samples and submitted to real‐time PCR (qPCR) and conventional PCR (cPCR) assays for Bartonella spp. targeting five genetic loci, followed by phylogenetic and genotype network analyses. Fifty‐one out of 208 liver samples (24.51%) were positive for Bartonella DNA in the ITS real‐time PCR assay [40 (78.43%) of them were from D. rotundus from 11 states, and 11 (21.57%) samples from D. ecaudata from three states. Eleven genotypes were found for each gltA and rpoB genes. Several ITS sequences detected in the present study clustered within the lineage that includes B. bacilliformis and B. ancachensis. The Bayesian phylogenetic inference based on the gltA gene positioned the obtained sequences in six different clades, closely related to Bartonella genotypes previously detected in D. rotundus and associated ectoparasites sampled in Latin America. On the other hand, the Bartonella rpoB genotypes clustered together with the ruminant species, B. schoenbuchensis and B. chomelii. The present study describes for the first time the molecular detection of Bartonella spp. in D. ecaudata bats. It also indicates that Bartonella spp. of vampire bats are genetically diverse and geographically widespread in Brazil.

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Section: Introductionmentioning

confidence: 99%

Genetic diversity ofBartonellaspp. in vampire bats from Brazil

André

Gutiérrez

Ikeda

et al. 2019

Transbound Emerg Dis

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“…Worldwide, domestic dogs can be infected with at least 10 Bartonella species . Bartonella vinsonii subsp .…”

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confidence: 99%

“…M embers of the genus Bartonella, fastidious gramnegative rod-shaped hemotropic and endotheliotropic bacteria, are important emerging pathogens in dogs and humans worldwide. [1][2][3] For the past 2 decades, an increasingly diverse number of Bartonella species have been isolated or detected using PCR in a wide range of animals including cats, dogs, and humans, as well as many wildlife reservoir and arthropod vector species. 4 Bartonella persists in erythrocytes and vascular endothelial cells, causing chronic relapsing bacteremia.…”

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confidence: 99%

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BartonellaSeroepidemiology in Dogs from North America, 2008–2014

Lashnits

Correa

Hegarty

et al. 2017

Veterinary Internal Medicne

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BackgroundImproved understanding of Bartonella species seroepidemiology in dogs may aid clinical decision making and enhance current understanding of naturally occurring arthropod vector transmission of this pathogen.ObjectivesTo identify demographic groups in which Bartonella exposure may be more likely, describe spatiotemporal variations in Bartonella seroreactivity, and examine co‐exposures to other canine vector‐borne diseases (CVBD).AnimalsA total of 15,451 serology specimens from dogs in North America were submitted to the North Carolina State University, College of Veterinary Medicine Vector Borne Disease Diagnostic Laboratory between January 1, 2008, and December 31, 2014.Methods Bartonella henselae, Bartonella koehlerae, and Bartonella vinsonii subspecies berkhoffii indirect fluorescent antibody (IFA) serology results, as well as results from a commercial assay kit screening for Dirofilaria immitis antigen and Ehrlichia species, Anaplasma phagocytophilum, and Borrelia burgdorferi antibodies, and Ehrlichia canis, Babesia canis, Babesia gibsoni, and Rickettsia species IFA results were reviewed retrospectively.ResultsOverall, 3.26% of dogs were Bartonella spp. seroreactive; B. henselae (2.13%) and B. koehlerae (2.39%) were detected more frequently than B. vinsonii subsp. berkhoffii (1.42%, P < 0.0001). Intact males had higher seroreactivity (5.04%) than neutered males (2.87%, P < 0.0001) or intact or spayed females (3.22%, P = 0.0003). Mixed breed dogs had higher seroreactivity (4.45%) than purebred dogs (3.02%, P = 0.0002). There was no trend in seasonal seroreactivity; geographic patterns supported broad distribution of exposure, and co‐exposure with other CVBD was common.Conclusions and Clinical Importance Bartonella spp. exposure was documented throughout North America and at any time of year. Male intact dogs, mixed breed dogs, and dogs exposed to other CVBD have higher seroreactivity to multiple Bartonella species.

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“…This success is characterized by the high prevalence of the infection and diversity of host species (Birtles, 2005;Kosoy et al, 2012). Currently, five (B. bovis, B. chomelii, B. schoenbuchensis, B. capreoli and B. melophagi) out of the 36 named Bartonella species/subspecies described have been associated with ruminants (Buffet et al, 2013;Breitschwerdt, 2017).…”

Section: Introductionmentioning

confidence: 99%

Molecular detection of Bartonella species and haemoplasmas in wild African buffalo (Syncerus caffer) in Mozambique, Africa

et al. 2018

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The African buffalo (Syncerus caffer), a mammal species whose population is declining, can play a role as a reservoir or carrier of a wide number of arthropod-borne pathogens. Translocation procedures have been used as an alternative approach for species conservation. However, the veterinary aspects of this sort of procedures are extremely important to minimize the impact on animal health. In order to detectBartonellaand haemoplasmas, two important group of bacterial that have an impact in both human and animal health, EDTA whole-blood samples were screened for the presence of these bacterial pathogens by molecular techniques. As a result, a molecular occurrence of 4.1 and 15.4% forBartonellaspp. and haemoplasmas, respectively, was reported among 97 wild buffaloes sampled during a translocation procedure from Marromeu to Gorongosa Reserve, Mozambique. Additionally, phylogenetic analyses of the obtained sequences were conducted. At least, three bovine-associated pathogens, namelyB. bovis,M. wenyoniiand ‘CandidatusM. haemobos’, as well as a probably newBartonellagenotype/species were detected inS. caffer.Further studies are needed in order to determine whether these bacterial species may cause impact in buffaloes and other sympatric ruminant species living in the release site.

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Bartonellosis, One Health and all creatures great and small

Cited by 31 publications

References 81 publications

Genetic diversity ofBartonellaspp. in vampire bats from Brazil

Genetic diversity ofBartonellaspp. in vampire bats from Brazil

BartonellaSeroepidemiology in Dogs from North America, 2008–2014

Molecular detection of Bartonella species and haemoplasmas in wild African buffalo (Syncerus caffer) in Mozambique, Africa

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