Bartholin gland carcinoma: A case report

Zhan, Ping; Li, Gang; Liu, Bin; Mao, Xiguang

doi:10.3892/ol.2014.2200

Cited by 12 publications

(23 citation statements)

References 12 publications

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“…Thus, cysts arising from the main duct are lined by transitional or squamous epithelium, whereas cysts originating in an acinus are lined by mucinous columnar epithelium. 6 In the case of our patient, it is lined by transitional epithelium.…”

Section: Bartholin's Cystmentioning

confidence: 63%

“…Recurrence is reported in approximately 20% of patients (ranging from 0% to 38%), and is more frequent after simple drainage. 6 Fistulization and marsupialization give a very low rate of recurrence, although the rate is probably underestimated due to a short follow-up time. 5,6 Antibiotics are frequently included in the treatment as a second-line therapy or in addition to surgical procedures.…”

Section: Bartholin's Cystmentioning

confidence: 99%

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Gigantic vulvar masses: a case series of benign large vulvar tumors

Bringas

Billod

2021

Int J Reprod Contracept Obstet Gynecol

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Benign vulvar masses are uncommon condition of the lower genital tract. To date, there is no recognized classification for benign tumors. Most of the vulvar tumors show no symptoms, unless large enough to be noted on self-examination. Presented are 3 cases of large vulvar masses. The first case is a Bartholin’s gland cyst in 56 years old, G5P4 (4014) with a 5-year history of gradually enlarging mass characterized as fleshy, approximately 16x14x12 cm, soft, non-tender located in the medial portion of the left labia majora. Grossly, the specimen consists of a unilocular cyst filled with serous fluid and had a smooth glistening inner capsule wall. The second case is a cellular angiofibroma in 61 years old, G0, who developed a fleshy mass, approximately 13x18x15 cm, soft, non-tender, attached to the left labia majora via a pedicle, which developed for 10 years. The specimen is described as an irregular mass with well circumscribed nodules with soft to rubbery, flesh cut surface. The third case is lipoblastoma-like tumor of the vulva in 31 years old, G2P2 (2002), who had a fleshy hypopigmented mass, approximately 15x12x10 cm, pendulous, soft, smooth, non-tender in the right inferolateral labia majora, which grew for 8 years. The specimen is characterized as an irregular mass partially overlain by skin with cut sections showing cream fatty lobulated surfaces. Benign vulvar masses may present similarly to one another hence careful and detailed assessment should be done. Histologic evaluation is critical in establishing an accurate diagnosis due to the fact that multiple diagnoses may have similar gross characteristics. Management is based on type and size of mass and symptomatology of patient.

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Section: Bartholin's Cystmentioning

confidence: 63%

Section: Bartholin's Cystmentioning

confidence: 99%

Gigantic vulvar masses: a case series of benign large vulvar tumors

Bringas

Billod

2021

Int J Reprod Contracept Obstet Gynecol

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“…There is less evidence for chemotherapy in ACCBG compared to adjuvant radiotherapy. A variety of chemotherapy regimens used include drugs such as paclitaxel, cyclophosphamide, cisplatin, methotrexate, doxorubicin, and 5-fluorouracil [10, 33, 34]. Chemotherapy regimens are usually used in conjunction with radiotherapy or after recurrence of ACCBGs after surgery and adjuvant radiotherapy treatment [10, 34].…”

Section: Discussionmentioning

confidence: 99%

“…Chemotherapy regimens are usually used in conjunction with radiotherapy or after recurrence of ACCBGs after surgery and adjuvant radiotherapy treatment [10, 34]. Immunotherapy has also been used with anecdotal reports of excellent response [33].…”

Section: Discussionmentioning

confidence: 99%

Adenoid Cystic Carcinoma of the Bartholin’s Gland: A Diagnostic Dilemma

Leow

Naing

et al. 2019

Case Reports in Obstetrics and Gynecology

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Adenoid cystic carcinomas of the Bartholin’s gland are extremely rare and are often misdiagnosed. There are currently no definite treatment guidelines. This article describes the case of a 33-year-old female who was managed at our centre for adenoid cystic carcinoma of the Bartholin’s gland. She presented with a prolonged history of a vulvar lesion which was eventually diagnosed as adenoid cystic carcinoma of the Bartholin’s gland. She was subsequently treated with wide local excision of the primary and inguinal lymph node dissection followed by adjuvant radiotherapy and chemotherapy. She had gross perineural invasion on MRI imaging. The present case highlights the diagnostic dilemma in this extremely rare cancer and the literature further explores the natural history and treatment options.

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“…Clinically, an enlargement in the greater vestibular glands in postmenopausal women should raise suspicion of the presence of a tumor, and biopsy is recommended. ACC presents as a not friable mass on speculum examination, with a size ranging from 0.5 to 4 cm, and with a deeply infiltrative pattern of growth [7,[16][17][18][19][20][21][22][23][24][25][26][27][28][29].…”

Section: Diagnosismentioning

confidence: 99%

Adenoid Cystic Carcinoma of Bartholin’s Gland: What Is the Best Approach?

et al. 2020

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Background and summary: Among all vulvar cancers, primary adenoid cystic carcinoma (ACC) of Bartholin's gland is a very rare tumor characterized by a slow growth, a high local aggressiveness, and a remarkable recurrence rate. Due to its rarity, treatment remains a challenge for oncologists and gynecological surgeons. Key message: The present paper reports clinical, radiological, and histological features of ACC of Bartholin's gland and reviews the literature data on the treatment options with a particular focus on the potential role of particle radiation therapy.

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Bartholin gland carcinoma: A case report

Cited by 12 publications

References 12 publications

Gigantic vulvar masses: a case series of benign large vulvar tumors

Gigantic vulvar masses: a case series of benign large vulvar tumors

Adenoid Cystic Carcinoma of the Bartholin’s Gland: A Diagnostic Dilemma

Adenoid Cystic Carcinoma of Bartholin’s Gland: What Is the Best Approach?

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