Barriers in Oligometastasis Care in Korea: Radiation Oncologists’ Perspectives

Chie, Eui Kyu; Rim, Chai Hong; Cho, Won Kyung; Ahn, Yong Chan

doi:10.4143/crt.2023.780

Cited by 1 publication

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References 8 publications

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“…However, local treatment may have socioeconomic benefits if the cost of managing progressive metastatic disease is reduced and a gain in patient quality of life or survival is obtained [37,38]. Furthermore, it is necessary to study the economic situation and insurance systems of various countries for the active treatment of oligometastasis [39].…”

Section: Discussionmentioning

confidence: 99%

Oligometastasis: Expansion of Curative Treatments in the Field of Oncology

Lim,

Rim

2023

Medicina

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Oligometastasis is defined as the presence of several limited metastatic lesions and is generally limited to three or fewer than five metastatic lesions. Previously, the treatment of metastatic cancer aimed to alleviate symptoms rather than cure them; however, the use of immunotherapy or targeted therapy has greatly improved patient life expectancy. Additionally, the effectiveness and safety of local treatment have recently been proven for oligometastatic cancers and have significantly improved patient survival and decreased recurrence rates. A few metastatic studies on lung cancer have demonstrated the usefulness of combining radiation therapy and immunotherapy. Recently, local and targeted therapy combinations have shown promising results in treating non-small cell lung cancer, predominantly caused by the epidermal growth factor receptor and anaplastic lymphoma kinase gene mutations, suggesting the potential of these new treatment strategies. It is well known that oligometastasis has better clinical results than polymetastasis; however, research on the biological profile of oligometastasis is still lacking. Studies using circulating tumor DNA and circulating tumor cells are at the initial stages of providing a better understanding of oligometastatic cancers, and the biological characteristics of these cancers may be revealed based on more diverse studies. With the development of these treatments, the prognosis for patients with oligometastatic cancers is steadily improving, and if the biological profile is revealed, customized treatment may be provided.

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Section: Discussionmentioning

confidence: 99%