BackgroundKnowledge translation platforms (KTPs) are intermediary organisations, initiatives or networks whose intent is to bridge the evidence into action divide. Strategies and tools include collaborative knowledge production, capacity building, information exchange and dialogue to facilitate relevant and timely engagement between researchers and decision-makers and other relevant stakeholders. With the wide range of definitions and descriptions of KTPs, there is a need to (a) provide a nuanced understanding of characteristics of KTPs and (b) assess and consolidate research methods used in mapping and evaluating KTPs to inform standardised process and impact evaluation. MethodsThis scoping review will follow the recommended and accepted methods for scoping reviews and reporting guidelines. Eligibility for inclusion is: any conceptual or empirical health-related qualitative, quantitative and/or mixed method studies including (a) definitions, descriptions and models or frameworks of KTPs (including those that do not self-identify as KTPs, e.g. university research centres) and (b) research methods for mapping and/or evaluating KTPs. Searches will be carried out in PubMed, Scopus, CINAHL, EMBASE, Global Health and Web of Science using search terms and synonyms for ‘knowledge translation platform’ and ‘evidence-informed decision-making’, without any date, language or geographic restrictions. Two reviewers will independently screen titles and abstracts. One reviewer will complete data extraction for all included studies, and another will check a sample of 50% of the included studies. All reviewers will be involved in the analysis process. The analysis and synthesis will provide: (a) an understanding of the various characteristics of KTPs; b) insight into characteristics or factors that make them resilient and/or adaptive to facilitate impact (i.e. influence policy and practice); and (c) an overview of the different methods for mapping and evaluating KTPs.DiscussionResults of the three aims above, will permit us to explore enhancing an existing matrix or framework for classifying KTPs or perhaps even developing a new framework for identifying and monitoring KTPs if necessary and relevant. This would be a helpful first step in establishing as well as evaluating KTPs.