Barium carbonate intoxication: an electrophysiological study

Kakar, Atul; Anand, Ish; Sethi, Prahlad K.

doi:10.1136/jnnp.65.4.606a

Cited by 4 publications

(3 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Barium toxicosis is a rare condition and is reported infrequently in the human medical literature. [4][5][6][10][11][12][13][14] To the authors' knowledge, barium toxicosis has not been reported in domestic animals. Barium salts are used in industry (glass, textiles, welding fluxes, and ceramic glazes) and as pesticides, depilatories, firework colorants, and radiographic contrast agents.…”

Section: Discussionmentioning

confidence: 80%

Barium toxicosis in a dog

Adam

Noble²,

Swift³

et al. 2010

javma

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 80%

Barium toxicosis in a dog

Adam

Noble²,

Swift³

et al. 2010

javma

View full text Add to dashboard Cite

show abstract

“…Intoxication – by way of ingestion, inhalation or cutaneous exposure – with soluble barium salts such as barium sulfide (1–4) (used in depilatories), barium carbonate (5–9) (a rodenticide) and barium chloride (10–13) is a rare but well‐known cause of severe hypokalemia. Neither in case reports (14) nor in animal experiments (15) is there a clear correlation between dose and severity of symptoms.…”

Section: Discussionmentioning

confidence: 99%

Acute barium nitrate intoxication treated by hemodialysis

Bahlmann

Lindwall

Persson

2005

Acta Anaesthesiol Scand

View full text Add to dashboard Cite

A 22-year-old male was admitted to hospital with diarrhea and vomiting, cardiac arrhythmias, severe hypokalemia and gradual onset of muscular weakness. A potassium infusion was started, but for several hours serum potassium remained low. Evidence of toxic ingestion was initially lacking. When it became clear -- after a considerable delay -- that the patient had ingested barium nitrate, hemodialysis was started. This resulted in rapid clinical improvement with correction of hypokalemia and restored muscular function. Intoxication with barium causes hypokalemia, arrhythmias, muscular weakness and paralysis, often requiring respiratory support. This patient presented with symptoms typical of severe barium intoxication, non-responsive to potassium supplementation. There are few published reports on the use of hemodialysis in barium poisoning. This case confirms the possible benefit of hemodialysis in severe cases, where potassium supplementation alone is insufficient.

show abstract

“…Barium may also have a direct effect on smooth muscle, since bariuminduced hypertension is not reversed by correcting plasma potassium levels (6). Barium could cause cardiac arrhythmias and digestive manifestations by a direct effect on cardiac and smooth muscles (6,7).…”

Section: Discussionmentioning

confidence: 99%

Acute Barium Intoxication and Hemodiafiltration

Koch¹,

Appoloni

Haufroid

et al. 2003

Journal of Toxicology: Clinical Toxicology

View full text Add to dashboard Cite

We report a case of severe hypokalemia and flaccid muscle paralysis following a suicide attempt associating the calcium channel blocker amlodipine, the antidepressant fluoxetine and barium carbonate. Despite rapid correction of severe, life-threatening hypokalemia, areflexic quadriplegia persisted, suggesting a direct effect of barium on muscle cells. Continuous veno-venous hemodiafiltration (CVVHDF) was initiated. We determined barium concentration in the urine, plasma, and hemodiafiltrate during CVVHDF. We subsequently calculated the amounts of barium eliminated both by the CVVHDF and the kidneys. CVVHDF triples the measured barium elimination, reduced serum barium half-life by a factor of three, stabilized serum potassium levels, and rapidly improved motor strength, with complete neurological recovery within 24 h. Presentation and treatment of barium intoxication are discussed.

show abstract

Barium carbonate intoxication: an electrophysiological study

Cited by 4 publications

References 5 publications

Barium toxicosis in a dog

Barium toxicosis in a dog

Acute barium nitrate intoxication treated by hemodialysis

Acute Barium Intoxication and Hemodiafiltration

Contact Info

Product

Resources

About