Bariatric Weight Loss Surgery Improves Systolic Function in Obese Patients With Heart Failure

Balakumaran, Kathir; Haddadin, Faris; Hamade, Hani; Lao, Nicole; Gaznabi, Safwan; Haddadin, Suhail; Garcia, Raul Angel; Schwab, Tracy S.; Shumiloff, Jennifer; Kaur, Babaljeet; Dhanvanthari, Sonya; Alamm, Chantal El

doi:10.1016/j.cpcardiol.2022.101231

Cited by 6 publications

(4 citation statements)

References 28 publications

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“…A study of adolescents with severe obesity found that adverse events after sleeve gastrectomy, were relatively common, with 21.5% of patients experiencing at least one adverse event within 30 days of surgery [49]. However, bariatric surgery has also been associated with a significantly lower incidence of major adverse cardiovascular events, all-cause mortality, cardiovascular mortality, coronary events, and heart failure hospitalizations in patients with severe obesity and cardiovascular disease [39][40][41]50,51]. Therefore, while adverse events are an important consideration in bariatric surgery, the surgery can also have significant benefits for certain patient populations.…”

Section: Discussionmentioning

confidence: 99%

“…The utilization of meta-analyses can aid in the determination of the optimal interventions for weight reduction and the amelioration of obesity-associated comorbidities, including hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia [53]. Bariatric surgery's long-term effects on all-cause and cardiovascular mortality can be assessed with their assistance [39][40][41]50,51]. Furthermore, meta-analytical studies can examine the potential impact of bariatric surgery on mitigating the likelihood of contracting various medical ailments, including colorectal cancer [52].…”

Section: Discussionmentioning

confidence: 99%

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Scientific and Public Interest in Bariatric Surgery for Obesity: The Italian Scenario

Mazzone,

Pezzino,

Sofia

et al. 2023

Gastrointestinal Disorders

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Background: Obesity is an escalating concern in our society. Bariatric surgery appears to be the only feasible alternative for severe obesity. This study aims to conduct an integrative analysis of the Italian context concerning bariatric surgery, with a specific focus on the surgical procedures of sleeve gastrectomy, mini-gastric bypass, and gastric bypass. Methods: The analysis is based on bibliometric data extracted from the Scopus database to find Italian publications in this field from 2012 to 2022. Along with scientific interest, it is essential to assess the level of public interest in these topics. Google Trends is the most extensively utilized free tool for the analysis of online behavior. Using Google Trends data, we analyzed the amount of internet volume searches (Relative Search Volume = RSV) for the Italian terms “sleeve gastrectomy”, “mini-gastric bypass” and “gastric bypass”, both temporally (from 2012 to 2022 years) and geographically. Furthermore, to illustrate the Italian landscape, we compared Google Trends data with data from the Italian registry “Società Italiana di Chirurgia dell’Obesità e delle malattie metaboliche” (SICOB), which includes information about bariatric surgery procedures performed in the country. Results: Over the past decade, there has been a significant increase in the scientific literature on sleeve gastrectomy, mini-gastric bypass, and gastric bypass surgeries in Italy. Google Trends data has shown an increase in online public interest in these surgical procedures, from 2012 to 2022. The examination of the Google Trends information combined with the SICOB data demonstrated a remarkable association between the two data sets. Conclusions: Bariatric surgery has increased quickly in Italy in terms of scientific research and surgical interventions. The analysis of Google Trends data in conjunction with data from SICOB has revealed an interesting correlation between the two datasets therefore, Google Trends can be useful for estimating the demand for bariatric surgical procedures.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Scientific and Public Interest in Bariatric Surgery for Obesity: The Italian Scenario

Mazzone,

Pezzino,

Sofia

et al. 2023

Gastrointestinal Disorders

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“…BMS has previously been demonstrated to improve systolic function for patients with established left ventricular dysfunction 23 , 24 . This was also demonstrated in our study with an improvement in both LVEF and NYHA classification.…”

Section: Discussionmentioning

confidence: 99%

“…This was also demonstrated in our study with an improvement in both LVEF and NYHA classification. The mechanisms behind this improvement are not fully understood but are likely multifactorial including reduced left ventricular hypertrophy, and resolution of metabolic dysfunction to improve cardiac muscle function and relaxation 23 . When it comes to the liver, although patients with potentially reversible stages of liver disease are known to derive benefits from BMS 25 , the picture for patients with more severe forms of hepatic dysfunction is less clear.…”

Section: Discussionmentioning

confidence: 99%

Safety outcomes of bariatric surgery in patients with advanced organ disease: the ONWARD study: a prospective cohort study

Singhal,

Cardoso,

Wiggins

et al. 2023

International Journal of Surgery

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Introduction: Increasing numbers of patients with advanced organ disease are being considered for Bariatric and Metabolic Surgery (BMS). There is no prospective study on the safety of BMS in these patients. This study aimed to capture outcomes for patients with advanced cardiac, renal, or liver disease undergoing BMS. Materials and Methods: This was a multinational, prospective cohort study on the safety of elective BMS in adults (≥18 y) with advanced disease of the heart, liver, or kidney. Results: Data on 177 patients with advanced diseases of heart, liver, or kidney were submitted by 75 centres in 33 countries. Mean age and Body Mass Index was 48.56±11.23 years and 45.55±7.35 kg/m 2 respectively. Laparoscopic sleeve gastrectomy was performed in 124 patients (70%). The 30-day morbidity and mortality were 15.9% (n=28) and 1.1% (n=2) respectively. 30-day morbidity was 16.4%, 11.7%, 20.5%, and 50.0% in patients with advanced heart (n=11/61), liver (n=8/68), kidney (n=9/44), and multi-organ disease (n=2/4) respectively. Cardiac patients with left ventricular ejection fraction ≤35% and New York Heart Association classification 3 or 4, liver patients with Model for End-Stage Liver Disease score ≥12, and patients with advanced renal disease not on dialysis were at increased risk of complications. Comparison with a propensity score matched cohort found advanced disease of the heart, liver, or kidney to be significantly associated with higher 30-day morbidity. Conclusion: Patients with advanced organ disease are at increased risk of 30-day morbidity following BMS. This prospective study quantifies that risk and identifies patients at the highest risk.

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The Effect of Bariatric Surgery on Patients with Heart Failure: a Systematic Review and Meta-analysis

Esparham,

Mehri,

Hadian

et al. 2023

OBES SURG

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Bariatric Weight Loss Surgery Improves Systolic Function in Obese Patients With Heart Failure

Cited by 6 publications

References 28 publications

Scientific and Public Interest in Bariatric Surgery for Obesity: The Italian Scenario

Scientific and Public Interest in Bariatric Surgery for Obesity: The Italian Scenario

Safety outcomes of bariatric surgery in patients with advanced organ disease: the ONWARD study: a prospective cohort study

The Effect of Bariatric Surgery on Patients with Heart Failure: a Systematic Review and Meta-analysis

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