Bariatric surgery and gene expression in the gut

Abstract

Bariatric surgery is an effective intervention strategy against severe obesity, resulting in sustained weight loss and reduction of comorbidities. Nutritional genomic changes appear in response to bariatric surgery, possibly due to adaptive gut response. Improved understanding of the molecular pathways modulated by this intervention may facilitate weight and comorbidities management.

Epigenetic fleas bite the genome in bone health, muscle strength, the gut, heart health and during ketogenesis

“…This acts as a receptor for the IF-B12 complex. In other words, although less vitamin B12 is captured by intrinsic factor in the stomach to form IF-B12, a greater proportion of this IF-B12 is extracted in the small intestine [12].…”