Bariatric Surgery and Diabetes

Spaniolas, Konstantinos; Pender, John R.; Cunningham, Emily; Pories, Walter J.

doi:10.1089/dia.2015.1509

Cited by 2 publications

(3 citation statements)

References 8 publications

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“…Studies have shown that post-surgery, the average levels of HbA1c are lowered and the clinical outcomes of comorbidities are much better than conventional and intensive medical therapy for obese diabetic patients [9]. There was also a significant decrease in insulin levels and fasting blood glucose postoperatively [10].…”

Section: Discussionmentioning

confidence: 99%

“…Since 2011, more randomized controlled trials were conducted and they showed that most obese patients were cured from type 2 diabetes after their bariatric surgery [6,7]. The most common forms of bariatric surgery include gastric banding (including adjustable and non adjustable bands), gastric bypass (Roux-en-Y gastric bypass), biliopancreatic diversion (duodenal switch) and gastric sleeve (gastroplasty) [8,9]. There is loss of life expectancy attributed to obesity.…”

Section: Introductionmentioning

confidence: 99%

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The Role of Bariatric Surgery in the Treatment of Type 2 Diabetes in Morbidly Obese Patients

Shoman¹

2017

JDMDC

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Obesity is a worldwide chronic epidemic and is a strong predictor of mortality. Its prevalence continues to increase despite public health efforts of awareness. With the rise in obesity and specifically morbid obesity worldwide, there has been a pronounced increase in obesity related metabolic disorders such as type 2 diabetes mellitus, hyperlipidemia, hypertension and some others. Reduction in weight is very important to control diabetes and one of the only measures that may cure diabetes and reduce weight loss is bariatric surgery. Bariatric surgery results in weight loss and the resolution of diabetes. Studies have shown that the effect of surgical weight loss has a more pronounced effect than diet controlled weight loss. This occurs due to several metabolic changes that occur in the body. The levels of incretins significantly rise including the rise of glucagon like peptide-1 and glucose-dependent insulinotropic polypeptide. In addition, PYY 3-36 and oxyntomodulin also rise post-surgery. On the other hand, there are reductions in branched chain amino acids, aromatic amino-acids phenylalanine and tyrosine.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Role of Bariatric Surgery in the Treatment of Type 2 Diabetes in Morbidly Obese Patients

Shoman¹

2017

JDMDC

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“…In STAMPEDE, the randomized study with the longest follow-up (3 years), there was a higher HbA1c reduction in the surgical group (-2.5%) than in the medical therapy group (-0.6%), which paralleled the greater reduction in weight (29). At 3 years, 5% of the medical therapy group, 38% of the gastric bypass group and 24% of the gastric sleeve group reached HbA1c levels of 6.0% or less.…”

Section: Randomized Control Studiesmentioning

confidence: 95%

Metabolic Surgery for Dabetes Mellitus between Benefits and Risks

Fica¹

2015

Acta Endo (Buc)

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Bariatric Surgery and Diabetes

Cited by 2 publications

References 8 publications

The Role of Bariatric Surgery in the Treatment of Type 2 Diabetes in Morbidly Obese Patients

The Role of Bariatric Surgery in the Treatment of Type 2 Diabetes in Morbidly Obese Patients

Metabolic Surgery for Dabetes Mellitus between Benefits and Risks

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