Banding patterns of the chromosomes of Miopithecus talapoin compared with Macaca mulatta and Cercopithecus aethiops

Ponsà, M.; Estop, A.; Miró, R.; Rubio, Andrew O.; Egozcue, J.

doi:10.1159/000131510

Cited by 17 publications

(2 citation statements)

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“…Catarrhini monkeys, and more specifically the Tribe Papionini, are characterized by the presence of highly conserved karyotypes in terms of diploid number and chromosome homologies [62, 63]. It has been described that species sharing the same karyotype (i.e., no major genome reshuffling) maintain the chromosomal distribution of meiotic crossover in conserved chromosomes on a broad scale (Mbp, the resolution provided by the in situ immunoflourescence detection of meiotic proteins) [64, 65].…”

Section: Resultsmentioning

confidence: 99%

“…It has been described that species sharing the same karyotype (i.e., no major genome reshuffling) maintain the chromosomal distribution of meiotic crossover in conserved chromosomes on a broad scale (Mbp, the resolution provided by the in situ immunoflourescence detection of meiotic proteins) [64, 65]. Therefore, we expect that the recombination pattern in Macaca and Cercocebus chromosomes (species that share the same karyotype and belong to the Tribe Papionini [62, 63]) are conserved at the Mbp resolution, thus allowing us to extrapolate the results obtained in both species, as previously described [64, 65]. In this context, and taking advantage of the EBRs detected in silico in the macaque genome, we subsequently studied the chromosomal distribution of meiotic crossover (COs – here exemplified as MLH1 foci ) in macaque chromosomes affected by inversions since their Catarrihini common ancestor (MMU5).…”

Section: Resultsmentioning

confidence: 99%

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Unraveling the effect of genomic structural changes in the rhesus macaque - implications for the adaptive role of inversions

et al. 2014

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BackgroundBy reshuffling genomes, structural genomic reorganizations provide genetic variation on which natural selection can work. Understanding the mechanisms underlying this process has been a long-standing question in evolutionary biology. In this context, our purpose in this study is to characterize the genomic regions involved in structural rearrangements between human and macaque genomes and determine their influence on meiotic recombination as a way to explore the adaptive role of genome shuffling in mammalian evolution.ResultsWe first constructed a highly refined map of the structural rearrangements and evolutionary breakpoint regions in the human and rhesus macaque genomes based on orthologous genes and whole-genome sequence alignments. Using two different algorithms, we refined the genomic position of known rearrangements previously reported by cytogenetic approaches and described new putative micro-rearrangements (inversions and indels) in both genomes. A detailed analysis of the rhesus macaque genome showed that evolutionary breakpoints are in gene-rich regions, being enriched in GO terms related to immune system. We also identified defense-response genes within a chromosome inversion fixed in the macaque lineage, underlying the relevance of structural genomic changes in evolutionary and/or adaptation processes. Moreover, by combining in silico and experimental approaches, we studied the recombination pattern of specific chromosomes that have suffered rearrangements between human and macaque lineages.ConclusionsOur data suggest that adaptive alleles – in this case, genes involved in the immune response – might have been favored by genome rearrangements in the macaque lineage.Electronic supplementary materialThe online version of this article (doi:10.1186/1471-2164-15-530) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Unraveling the effect of genomic structural changes in the rhesus macaque - implications for the adaptive role of inversions

et al. 2014

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2020

Atlas of Mammalian Chromosomes

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Banding patterns of the chromosomes of Presbytis cristatus pyrrhus and P. obscurus

Ponsà¹,

Boer²,

Egozcue³

1983

American J Primatol

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The G-and Q-bands and the location of the nucleolar organizer regions (NOR) in the chromosomes of Presbytis obscurus and the Q-and C-bands of l? cristatus pyrrhus are described. Their chromosomes are compared to those of Macaca mulatta and to other Cercopithecidae and Hylobatidae. The origin of the two different banding patterns of pair no. 1 in our specimen of €? cristatus pyrrhus is discussed.

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Banding patterns of the chromosomes of Miopithecus talapoin compared with Macaca mulatta and Cercopithecus aethiops

Abstract: The G-, C-, and Q-banding and NOR patterns of the chromosomes of Miopithecus talapoin are described. G-banding patterns are compared with those of Macaca mulatta and Cercopithecus aethiops which show large homoeologies.

Cited by 17 publications

References 4 publications

Unraveling the effect of genomic structural changes in the rhesus macaque - implications for the adaptive role of inversions

Unraveling the effect of genomic structural changes in the rhesus macaque - implications for the adaptive role of inversions

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Banding patterns of the chromosomes of Presbytis cristatus pyrrhus and P. obscurus

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