Bandeiraea Simplicifolia Isolectin B4 Binds Mast Cells in Human Skin and this Latter Binding is Up-Regulated in Patients with Atopic Dermatitis and Stinging
Abstract:The causes of sensitive skin, a common problem in patients with acne rosacea or atopic dermatitis, and even in individuals without obvious skin disease, remain unclear. The density of nerve fibers, levels of neuropeptides as well as the nature and number of mast cells may play a role in this connection. Unmyelinated nociceptive neurons mediate most of the sensation from the skin, and a large part of these neurons are characterized by their ability to bind the lectin Banderiaea simlicifolia isolectin IB4 (IB4).… Show more
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