Bamboo shoot fiber prevents obesity in mice by modulating the gut microbiota

Abstract

Dietary fiber has been shown to prevent high-fat diet induced obesity through modulating the gut microbiota; however, quality difference in fiber type is largely unknown. We performed a 6 week study on C57BL/6J mice fed a macronutrient matched high-fat diet with different fiber types including cellulose (HFC), bamboo shoot fiber (HFBS) and several other commonly consumed fibers. Our results showed that the HFBS group exhibited the lowest weight gain among all diet groups and had improved lipid profiles and glycemic control compared with the HFC group. As revealed by 16S rRNA gene sequencing, loss of diversity in the gut microbiota induced by the HFC diet was largely prevented by the HFBS diet. Moreover, compared with the HFC diet, the HFBS diet resulted in markedly increased relative abundance of Bacteroidetes and strong inhibition of Verrucomicrobia, two divisions strongly correlated with body weight. In conclusion, the present study provides evidence of a quality difference among different types of dietary fibers and shows that bamboo shoot fiber is the most effective in suppressing high-fat diet induced obesity. Our findings indicate that bamboo shoot fiber is a potential prebiotic fiber which modulates the gut microbiota and improves host metabolism.

Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice

“…In addition, dietary fiber also causes metabolic effects by decreasing fat storage because of increased satiety [9]. Similar results are reported when bamboo shoot fiber is used in mice test [12].…”

“…Similarly, recent studies demonstrate that wheat fiber and phytochemicals isolated from wheat bran suppress body weight gain in high-fat dietfed mice [11]. In addition, bamboo shoot fiber also shows an effective role in suppressing high-fat diet-induced obesity than soluble fibers [12]. On the contrary, Weitkunat et al [13] reported that dietary fibers are discussed as factors influencing diet-induced obesity and energy homeostasis.…”

Agaro-Oligosaccharides Regulate Gut Microbiota and Adipose Tissue Accumulation in Mice

“…Akkermansia muciniphila is an intestinal mucindegrading bacterium (43). Li et al (44) reported that administration of bamboo shoots reduced the body weight gain and fat mass in high-fat-diet-fed mice. The relative abundance of Akkermansia was lower in the bamboo shoot-fed group.…”

Western diets, gut dysbiosis, and metabolic diseases: Are they linked?

“…55 For instance, bamboo shoot fiber was shown to prevent HFD-induced weight gain and insulin resistance in mice, and concurrently altered microbial composition including increased relative abundance of Bacteroidetes and decreased abundance of Firmicutes. 56 Inclusion of 10% (w/w) short chain FOS in HFDs (60% kcal from fat) altered microbial composition and function as measured by changes in metabolic byproducts of the microbiome. 57 In another report, maize-derived feruloylated oligo-and polysaccharides (FOPS) included at 5% (w/w) of a HFD (60% kcal from fat) improved outcomes in a subset of mice that correlated with changes in microbial structure.…”